Illicaborins A-C, three prenylated C6-C3 compounds from the fruits of Illicium arborescens

Ya Xu Lin; Ahmed Eid Fazary; Shun Ying Chen; Ching Te Chien; Yao Haur Kuo; Shiow Yunn Sheu; Ya Ching Shen

doi:10.1016/j.foodchem.2010.05.069

Illicaborins A-C, three prenylated C₆-C₃ compounds from the fruits of Illicium arborescens

Ya Xu Lin, Ahmed Eid Fazary, Shun Ying Chen, Ching Te Chien, Yao Haur Kuo, Shiow Yunn Sheu, Ya Ching Shen

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Three new prenylated C₆-C₃ compounds, illicaborins A-C (1-3), were isolated and characterised from the fruits of Illicium arborescens Hayata. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, ¹H NMR, ¹³C NMR, ¹H-¹H COSY, HMQC, HMBC, and NOESY) including molecular modelling. Compound 1 possesses a new carbon skeleton having a prenylated C₆-C₃ skeleton with an additional CH₂OH group at the C-2 position. The cytotoxic activities of compounds 1-3 were tested and evaluated against Hep-2, Daoy, MCF-7 and WiDr tumour cell lines.

Original language	English
Pages (from-to)	1105-1111
Number of pages	7
Journal	Food Chemistry
Volume	123
Issue number	4
DOIs	https://doi.org/10.1016/j.foodchem.2010.05.069
Publication status	Published - Dec 2010

Keywords

Cytotoxic activities
Illicaborins
Illicium arborescens

ASJC Scopus subject areas

Analytical Chemistry
Food Science

Access to Document

10.1016/j.foodchem.2010.05.069

Cite this

@article{b435fcc3be5f498084d660d25c29956c,

title = "Illicaborins A-C, three prenylated C6-C3 compounds from the fruits of Illicium arborescens",

abstract = "Three new prenylated C6-C3 compounds, illicaborins A-C (1-3), were isolated and characterised from the fruits of Illicium arborescens Hayata. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, HMBC, and NOESY) including molecular modelling. Compound 1 possesses a new carbon skeleton having a prenylated C6-C3 skeleton with an additional CH2OH group at the C-2 position. The cytotoxic activities of compounds 1-3 were tested and evaluated against Hep-2, Daoy, MCF-7 and WiDr tumour cell lines.",

keywords = "Cytotoxic activities, Illicaborins, Illicium arborescens",

author = "Lin, {Ya Xu} and Fazary, {Ahmed Eid} and Chen, {Shun Ying} and Chien, {Ching Te} and Kuo, {Yao Haur} and Sheu, {Shiow Yunn} and Shen, {Ya Ching}",

note = "Funding Information: The authors thank the National Science Council , Republic of China, for financial support ( NSC96-2323-B-002-018 ). Appendix A ",

year = "2010",

month = dec,

doi = "10.1016/j.foodchem.2010.05.069",

language = "English",

volume = "123",

pages = "1105--1111",

journal = "Food Chemistry",

issn = "0308-8146",

publisher = "Elsevier Ltd",

number = "4",

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TY - JOUR

T1 - Illicaborins A-C, three prenylated C6-C3 compounds from the fruits of Illicium arborescens

AU - Lin, Ya Xu

AU - Fazary, Ahmed Eid

AU - Chen, Shun Ying

AU - Chien, Ching Te

AU - Kuo, Yao Haur

AU - Sheu, Shiow Yunn

AU - Shen, Ya Ching

N1 - Funding Information: The authors thank the National Science Council , Republic of China, for financial support ( NSC96-2323-B-002-018 ). Appendix A

PY - 2010/12

Y1 - 2010/12

N2 - Three new prenylated C6-C3 compounds, illicaborins A-C (1-3), were isolated and characterised from the fruits of Illicium arborescens Hayata. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, HMBC, and NOESY) including molecular modelling. Compound 1 possesses a new carbon skeleton having a prenylated C6-C3 skeleton with an additional CH2OH group at the C-2 position. The cytotoxic activities of compounds 1-3 were tested and evaluated against Hep-2, Daoy, MCF-7 and WiDr tumour cell lines.

AB - Three new prenylated C6-C3 compounds, illicaborins A-C (1-3), were isolated and characterised from the fruits of Illicium arborescens Hayata. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, HMBC, and NOESY) including molecular modelling. Compound 1 possesses a new carbon skeleton having a prenylated C6-C3 skeleton with an additional CH2OH group at the C-2 position. The cytotoxic activities of compounds 1-3 were tested and evaluated against Hep-2, Daoy, MCF-7 and WiDr tumour cell lines.

KW - Cytotoxic activities

KW - Illicaborins

KW - Illicium arborescens

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