Ictal-interictal comparison of FDG-PET findings in sporadic hemiplegic migraine

Po Tso Lin, Syu Jyun Peng, Hsiang Yu Yu

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Purpose: Sporadic hemiplegic migraine (SHM) is characterized by a prolonged motor aura that accompanies a migraine attack, and its underlying pathophysiology remains unclear. Functional image during the event can help to explore the mechanism. Case report: We report a finding of 18-fluorodeoxyglucose positron emission tomography (FDG-PET) in a 15-year-old female with SHM. She presented with recurrent right arm weakness and pain with migrainous headache. A video electroencephalogram showed no evidence of epilepsy during the events. Subtraction of ictal-interictal FDG-PET coregistered to magnetic resonance imaging was performed for the image analysis. In comparison with the interictal state, the FDG-PET image showed decreased glucose metabolism in the bilateral dorsal lateral frontal cortices and bilateral occipital cortices, whereas increased metabolism in the left precentral motor cortex and right premotor cortex. Conclusion: These findings reveal an increase in metabolism in the motor cortex during general cortical dysfunction in the frontal and occipital cortices in SHM.

Original languageEnglish
Pages (from-to)78-83
Number of pages6
JournalActa Neurologica Taiwanica
Issue number3
Publication statusPublished - Sept 2019


  • Hemiplegic migraine
  • Migraine
  • Positron emission tomography

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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