Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Yuan Bin Cheng, Ahmed Eid Fazary, Yu Chi Lin, I. Wen Lo, Seow Chin Ong, Shun Ying Chen, Ching Te Chien, Yen Jung Lin, Wan Wan Lin, Ya Ching Shen

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.

Original languageEnglish
Pages (from-to)727-734
Number of pages8
JournalNatural Product Research
Issue number8
Publication statusPublished - Apr 1 2013


  • anti-inflammatory activity
  • Hypericum nakamurai
  • phloroglucinols

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Analytical Chemistry
  • Organic Chemistry


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