Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Yuan Bin Cheng; Ahmed Eid Fazary; Yu Chi Lin; I. Wen Lo; Seow Chin Ong; Shun Ying Chen; Ching Te Chien; Yen Jung Lin; Wan Wan Lin; Ya Ching Shen

doi:10.1080/14786419.2012.695365

Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Yuan Bin Cheng, Ahmed Eid Fazary, Yu Chi Lin, I. Wen Lo, Seow Chin Ong, Shun Ying Chen, Ching Te Chien, Yen Jung Lin, Wan Wan Lin, Ya Ching Shen

Graduate Institute of Medical Sciences

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.

Original language	English
Pages (from-to)	727-734
Number of pages	8
Journal	Natural Product Research
Volume	27
Issue number	8
DOIs	https://doi.org/10.1080/14786419.2012.695365
Publication status	Published - Apr 1 2013

Keywords

anti-inflammatory activity
Hypericum nakamurai
phloroglucinols

ASJC Scopus subject areas

Plant Science
Biochemistry
Analytical Chemistry
Organic Chemistry

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10.1080/14786419.2012.695365

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title = "Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai",

abstract = "Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.",

keywords = "anti-inflammatory activity, Hypericum nakamurai, phloroglucinols",

author = "Cheng, {Yuan Bin} and Fazary, {Ahmed Eid} and Lin, {Yu Chi} and Lo, {I. Wen} and Ong, {Seow Chin} and Chen, {Shun Ying} and Chien, {Ching Te} and Lin, {Yen Jung} and Lin, {Wan Wan} and Shen, {Ya Ching}",

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AU - Cheng, Yuan Bin

AU - Fazary, Ahmed Eid

AU - Lin, Yu Chi

AU - Lo, I. Wen

AU - Ong, Seow Chin

AU - Chen, Shun Ying

AU - Chien, Ching Te

AU - Lin, Yen Jung

AU - Lin, Wan Wan

AU - Shen, Ya Ching

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Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Abstract

Keywords

ASJC Scopus subject areas

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