Abstract
Original language | English |
---|---|
Pages (from-to) | 202-214 |
Number of pages | 13 |
Journal | Schizophrenia Research |
Volume | 127 |
Issue number | 1-3 |
DOIs | |
Publication status | Published - 2011 |
Externally published | Yes |
Keywords
- Auditory cortex
- Auditory verbal hallucinations
- Resting state
- Schizophrenia
- anterior cingulate
- auditory cortex
- auditory stimulation
- auditory verbal hallucination
- delusion
- diagonal band of Broca
- evoked auditory response
- hallucination
- human
- middle temporal gyrus
- mismatch negativity
- neuroimaging
- neuromodulation
- phenomenology
- prefrontal cortex
- priority journal
- review
- schizophrenia
- superior temporal gyrus
- visual hallucination
- working memory
- Auditory Cortex
- Brain Mapping
- Hallucinations
- Humans
- Neural Pathways
- Rest
- Verbal Behavior
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In: Schizophrenia Research, Vol. 127, No. 1-3, 2011, p. 202-214.
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - How can the brain's resting state activity generate hallucinations? A 'resting state hypothesis' of auditory verbal hallucinations
AU - Northoff, Georg
AU - Qin, Pengmin
N1 - 被引用次數:50 Export Date: 31 March 2016 CODEN: SCRSE 通訊地址: Northoff, G.; Mind Brain Imaging and Neuroethics, Institute of Mental Health Research (IMHR), 1145 Carling Avenue, Ottawa, ON K1Z 7K4, Canada; 電子郵件: [email protected] 參考文獻: Allen, P., Aleman, A., McGuire, P.K., Inner speech models of auditory verbal hallucinations: evidence from behavioural and neuroimaging studies (2007) Int. Rev. Psychiatry, 19 (4), pp. 407-415; Allen, P., Amaro, E., Fu, C.H., Williams, S.C., Brammer, M.J., Johns, L.C., McGuire, P.K., Neural correlates of the misattribution of speech in schizophrenia (2007) Br. J. Psychiatry, 190, pp. 162-169; Allen, P., Laroi, F., McGuire, P.K., Aleman, A., The hallucinating brain: a review of structural and functional neuroimaging studies of hallucinations (2008) Neurosci. Biobehav. 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PY - 2011
Y1 - 2011
N2 - While several hypotheses about the neural mechanisms underlying auditory verbal hallucinations (AVH) have been suggested, the exact role of the recently highlighted intrinsic resting state activity of the brain remains unclear. Based on recent findings, we therefore developed what we call the 'resting state hypotheses' of AVH. Our hypothesis suggest that AVH may be traced back to abnormally elevated resting state activity in auditory cortex itself, abnormal modulation of the auditory cortex by anterior cortical midline regions as part of the default-mode network, and neural confusion between auditory cortical resting state changes and stimulus-induced activity. We discuss evidence in favour of our 'resting state hypothesis' and show its correspondence with phenomenological accounts. © 2010 Elsevier B.V.
AB - While several hypotheses about the neural mechanisms underlying auditory verbal hallucinations (AVH) have been suggested, the exact role of the recently highlighted intrinsic resting state activity of the brain remains unclear. Based on recent findings, we therefore developed what we call the 'resting state hypotheses' of AVH. Our hypothesis suggest that AVH may be traced back to abnormally elevated resting state activity in auditory cortex itself, abnormal modulation of the auditory cortex by anterior cortical midline regions as part of the default-mode network, and neural confusion between auditory cortical resting state changes and stimulus-induced activity. We discuss evidence in favour of our 'resting state hypothesis' and show its correspondence with phenomenological accounts. © 2010 Elsevier B.V.
KW - Auditory cortex
KW - Auditory verbal hallucinations
KW - Resting state
KW - Schizophrenia
KW - anterior cingulate
KW - auditory cortex
KW - auditory stimulation
KW - auditory verbal hallucination
KW - delusion
KW - diagonal band of Broca
KW - evoked auditory response
KW - hallucination
KW - human
KW - middle temporal gyrus
KW - mismatch negativity
KW - neuroimaging
KW - neuromodulation
KW - phenomenology
KW - prefrontal cortex
KW - priority journal
KW - review
KW - schizophrenia
KW - superior temporal gyrus
KW - visual hallucination
KW - working memory
KW - Auditory Cortex
KW - Brain Mapping
KW - Hallucinations
KW - Humans
KW - Neural Pathways
KW - Rest
KW - Verbal Behavior
U2 - 10.1016/j.schres.2010.11.009
DO - 10.1016/j.schres.2010.11.009
M3 - Article
C2 - 21146961
SN - 0920-9964
VL - 127
SP - 202
EP - 214
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -