Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Hong Yuan Lian; Ming Hu; Chia Hung Liu; Yusuke Yamauchi; Kevin C.W. Wu

doi:10.1039/c2cc31708g

Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Hong Yuan Lian, Ming Hu, Chia Hung Liu, Yusuke Yamauchi, Kevin C.W. Wu

Research output: Contribution to journal › Article › peer-review

167 Citations (Scopus)

Abstract

Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC₅₀ > 1000 μg mL⁻¹) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

Original language	English
Pages (from-to)	5151-5153
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	42
DOIs	https://doi.org/10.1039/c2cc31708g
Publication status	Published - Apr 30 2012

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c2cc31708g

Cite this

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title = "Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery",

abstract = "Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.",

author = "Lian, {Hong Yuan} and Ming Hu and Liu, {Chia Hung} and Yusuke Yamauchi and Wu, {Kevin C.W.}",

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AU - Lian, Hong Yuan

AU - Hu, Ming

AU - Liu, Chia Hung

AU - Yamauchi, Yusuke

AU - Wu, Kevin C.W.

PY - 2012/4/30

Y1 - 2012/4/30

N2 - Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

AB - Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC50 > 1000 μg mL−1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

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DO - 10.1039/c2cc31708g

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JO - Chemical Communications

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Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Abstract

ASJC Scopus subject areas

UN SDGs

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