High-resolution computed tomography in assessment of patients with emphysema

Jeng Shing Wang, Jaw Ming Cherng, Daw Shyong Perng, Hong Shen Lee, Sophie Wang

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


OBJECTIVE: To assess whether high-resolution computed tomography (HRCT) variables are as good as other known clinical variables in grading emphysema patients. METHODS: A detailed clinical history was taken and physical examination performed. We performed serum study, lung function testing, and HRCT scanning to assess emphysema. Mean lung density, the attenuation value separating the least 15% of pixels (PERC15), the percentage of the relative area of the lungs with attenuation values <-950 Hounsfield units (HU) (RA950), and histogram analysis were calculated from computerized data. RESULTS: The final analysis was based on data from 92 subjects, and they were moderately emphysematous (mean lung density was -877 ± 23 HU, PERC15 was -953 ± 21 HU, and RA950 was 16 ± 5%). There was a significant difference regarding subjective emphysema severity in the St George's Respiratory Questionnaire, smoking history, FEV1, C-reactive protein, age, and body mass index (P 1, C-reactive protein, age, and body mass index) (P

Original languageEnglish
Pages (from-to)614-622
Number of pages9
JournalRespiratory Care
Issue number4
Publication statusPublished - Apr 1 2013


  • Emphysema
  • Emphysema severity
  • High-resolution computed tomography
  • Mean lung density

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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