High-resolution computed tomography in assessment of patients with emphysema

Jeng Shing Wang; Jaw Ming Cherng; Daw Shyong Perng; Hong Shen Lee; Sophie Wang

doi:10.4187/respcare.01691

High-resolution computed tomography in assessment of patients with emphysema

Jeng Shing Wang, Jaw Ming Cherng, Daw Shyong Perng, Hong Shen Lee, Sophie Wang

College of Medicine

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

OBJECTIVE: To assess whether high-resolution computed tomography (HRCT) variables are as good as other known clinical variables in grading emphysema patients. METHODS: A detailed clinical history was taken and physical examination performed. We performed serum study, lung function testing, and HRCT scanning to assess emphysema. Mean lung density, the attenuation value separating the least 15% of pixels (PERC15), the percentage of the relative area of the lungs with attenuation values <-950 Hounsfield units (HU) (RA950), and histogram analysis were calculated from computerized data. RESULTS: The final analysis was based on data from 92 subjects, and they were moderately emphysematous (mean lung density was -877 ± 23 HU, PERC15 was -953 ± 21 HU, and RA950 was 16 ± 5%). There was a significant difference regarding subjective emphysema severity in the St George's Respiratory Questionnaire, smoking history, FEV₁, C-reactive protein, age, and body mass index (P 1, C-reactive protein, age, and body mass index) (P

Original language	English
Pages (from-to)	614-622
Number of pages	9
Journal	Respiratory Care
Volume	58
Issue number	4
DOIs	https://doi.org/10.4187/respcare.01691
Publication status	Published - Apr 1 2013

Keywords

Emphysema
Emphysema severity
High-resolution computed tomography
Mean lung density

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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10.4187/respcare.01691

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title = "High-resolution computed tomography in assessment of patients with emphysema",

abstract = "OBJECTIVE: To assess whether high-resolution computed tomography (HRCT) variables are as good as other known clinical variables in grading emphysema patients. METHODS: A detailed clinical history was taken and physical examination performed. We performed serum study, lung function testing, and HRCT scanning to assess emphysema. Mean lung density, the attenuation value separating the least 15% of pixels (PERC15), the percentage of the relative area of the lungs with attenuation values <-950 Hounsfield units (HU) (RA950), and histogram analysis were calculated from computerized data. RESULTS: The final analysis was based on data from 92 subjects, and they were moderately emphysematous (mean lung density was -877 ± 23 HU, PERC15 was -953 ± 21 HU, and RA950 was 16 ± 5%). There was a significant difference regarding subjective emphysema severity in the St George's Respiratory Questionnaire, smoking history, FEV1, C-reactive protein, age, and body mass index (P 1, C-reactive protein, age, and body mass index) (P",

keywords = "Emphysema, Emphysema severity, High-resolution computed tomography, Mean lung density",

author = "Wang, {Jeng Shing} and Cherng, {Jaw Ming} and Perng, {Daw Shyong} and Lee, {Hong Shen} and Sophie Wang",

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doi = "10.4187/respcare.01691",

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T1 - High-resolution computed tomography in assessment of patients with emphysema

AU - Wang, Jeng Shing

AU - Cherng, Jaw Ming

AU - Perng, Daw Shyong

AU - Lee, Hong Shen

AU - Wang, Sophie

PY - 2013/4/1

Y1 - 2013/4/1

N2 - OBJECTIVE: To assess whether high-resolution computed tomography (HRCT) variables are as good as other known clinical variables in grading emphysema patients. METHODS: A detailed clinical history was taken and physical examination performed. We performed serum study, lung function testing, and HRCT scanning to assess emphysema. Mean lung density, the attenuation value separating the least 15% of pixels (PERC15), the percentage of the relative area of the lungs with attenuation values <-950 Hounsfield units (HU) (RA950), and histogram analysis were calculated from computerized data. RESULTS: The final analysis was based on data from 92 subjects, and they were moderately emphysematous (mean lung density was -877 ± 23 HU, PERC15 was -953 ± 21 HU, and RA950 was 16 ± 5%). There was a significant difference regarding subjective emphysema severity in the St George's Respiratory Questionnaire, smoking history, FEV1, C-reactive protein, age, and body mass index (P 1, C-reactive protein, age, and body mass index) (P

AB - OBJECTIVE: To assess whether high-resolution computed tomography (HRCT) variables are as good as other known clinical variables in grading emphysema patients. METHODS: A detailed clinical history was taken and physical examination performed. We performed serum study, lung function testing, and HRCT scanning to assess emphysema. Mean lung density, the attenuation value separating the least 15% of pixels (PERC15), the percentage of the relative area of the lungs with attenuation values <-950 Hounsfield units (HU) (RA950), and histogram analysis were calculated from computerized data. RESULTS: The final analysis was based on data from 92 subjects, and they were moderately emphysematous (mean lung density was -877 ± 23 HU, PERC15 was -953 ± 21 HU, and RA950 was 16 ± 5%). There was a significant difference regarding subjective emphysema severity in the St George's Respiratory Questionnaire, smoking history, FEV1, C-reactive protein, age, and body mass index (P 1, C-reactive protein, age, and body mass index) (P

KW - Emphysema

KW - Emphysema severity

KW - High-resolution computed tomography

KW - Mean lung density

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High-resolution computed tomography in assessment of patients with emphysema

Abstract

Keywords

ASJC Scopus subject areas

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