Heroin-induced spongiform leukoencephalopathy: Value of diffusion MR imaging

Cheng Yu Chen, Kwo Wei Lee, Chueng Chen Lee, Shy Chi Chin, Hsiao Wen Chung, Robert A. Zimmerman

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)


The diffusion-weighted (DW) magnetic resonance (MR) imaging findings of a patient with subacute stage of heroin-induced vacuolating myelinopathy are reported. The diffuse decrease of apparent diffusion coefficient (ADC) of the white matter on DW imaging is attributed to restricted water diffusion, which is known to be caused by fluid entrapment within the myelin lamellae without demyelination.

Original languageEnglish
Pages (from-to)735-737
Number of pages3
JournalJournal of Computer Assisted Tomography
Issue number5
Publication statusPublished - 2000
Externally publishedYes


  • Diffusion-weighted MRI
  • Heroin intoxication
  • Myelinopathy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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