TY - JOUR
T1 - Hepatoprotective effects of Taiwan folk medicine
T2 - Ixeris chinensis (Thunb.) Nak. on experimental liver injuries.
AU - Lin, Song-Chow
AU - Lin, C. C.
AU - Lin, Y. H.
AU - Yao, C. J.
PY - 1994
Y1 - 1994
N2 - The hepatoprotective effects of Ixeris chinensis (Thunb.) Nak. were studied on acute hepatitis induced in mice by a single dose of carbon tetrachloride (31.25 microliters/kg, ip) or acetaminophen (600 mg/kg, ip), and in rats by a single dose of beta-D-galactosamine (188 mg/kg, ip). Hepatoprotective activity was monitored by estimating the serum transaminases (SGOT and SGPT) levels and histopathological changes in the livers of experimental animals. The Ixeris chinensis (Thunb.) Nak. extracts significantly inhibited the acute elevation of serum transaminases. Histopathologically, the crude I. chinensis extract significantly ameliorated hepatotoxin-induced histopathological changes in the livers of experimental animals. All pharmacological and histopathological effects of Ixeris chinensis (Thunb.) Nak. were compared with Bupleurum chinense DC., which has been previously reported as a treatment herb for hepatitis.
AB - The hepatoprotective effects of Ixeris chinensis (Thunb.) Nak. were studied on acute hepatitis induced in mice by a single dose of carbon tetrachloride (31.25 microliters/kg, ip) or acetaminophen (600 mg/kg, ip), and in rats by a single dose of beta-D-galactosamine (188 mg/kg, ip). Hepatoprotective activity was monitored by estimating the serum transaminases (SGOT and SGPT) levels and histopathological changes in the livers of experimental animals. The Ixeris chinensis (Thunb.) Nak. extracts significantly inhibited the acute elevation of serum transaminases. Histopathologically, the crude I. chinensis extract significantly ameliorated hepatotoxin-induced histopathological changes in the livers of experimental animals. All pharmacological and histopathological effects of Ixeris chinensis (Thunb.) Nak. were compared with Bupleurum chinense DC., which has been previously reported as a treatment herb for hepatitis.
UR - http://www.scopus.com/inward/record.url?scp=0028696227&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028696227&partnerID=8YFLogxK
M3 - Article
C2 - 7872236
AN - SCOPUS:0028696227
SN - 0192-415X
VL - 22
SP - 243
EP - 254
JO - American Journal of Chinese Medicine
JF - American Journal of Chinese Medicine
IS - 3-4
ER -
