Guidelines for COVID-19 Laboratory Testing for Emergency Departments From the New Diagnostic Technology Team of the Taiwan Society of Emergency Medicine

Chien Chang Lee, Yi Tzu Lee, Chih Hung Wang, I. Min Chiu, Weide Tsai, Yan Ren Lin, Chih Huang Li, Chin Wang Hsu, Pei Fang Lai, Jiann Hwa Chen, Jeffrey Che Hung Tsai, Shih Hung Tsai, Chorng Kuang How

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

COVID-19 tests have different turnaround times (TATs), accuracy levels, and limitations, which emergency physicians should be aware of. Nucleic acid amplification tests (NAATs) can be divided into standard high throughput tests and rapid molecular diagnostic tests at the point of care (POC). The standard NAAT has the advantages of high throughput and high accuracy with a TAT of 3-4 hours. The POC molecular test has the same advantages of high accuracy as standard high throughput PCR, but can be done in 13-45 minutes. Roche cobas Liat is the most commonly used machine in Taiwan, displaying 99%-100% sensitivity and 100% specificity, respectively. Abbott ID NOW is an isothermal PCR-based POC machine with a sensitivity of 79% and a specificity of 100%. A high rate of false positives and false negatives is associated with rapid antigen testing. Antibody testing is mostly used as part of public health surveys and for testing for immunity.

Original languageEnglish
Pages (from-to)45-52
Number of pages8
JournalJournal of Acute Medicine
Volume12
Issue number2
DOIs
Publication statusPublished - Jun 1 2022

Keywords

  • COVID-19
  • nucleic acid amplification testing
  • point-of-care testing
  • rapid point-of-care molecular testing

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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