Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

Min Huei Hsu; Chia An Hsu; Shih Chung Lai; Ju Chuan Yen

doi:10.3390/ijerph191610142

Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

Min Huei Hsu, Chia An Hsu, Shih Chung Lai, Ju Chuan Yen

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.

Original language	English
Article number	10142
Journal	International journal of environmental research and public health
Volume	19
Issue number	16
DOIs	https://doi.org/10.3390/ijerph191610142
Publication status	Published - Aug 2022

Keywords

age-related macular degeneration
gout
Taiwan National Health Insurance Research Database

ASJC Scopus subject areas

Pollution
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3390/ijerph191610142

Cite this

@article{263cc120eac4463dba30f019e2dda311,

title = "Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan",

abstract = "The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan{\textquoteright}s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.",

keywords = "age-related macular degeneration, gout, Taiwan National Health Insurance Research Database",

author = "Hsu, {Min Huei} and Hsu, {Chia An} and Lai, {Shih Chung} and Yen, {Ju Chuan}",

note = "Funding Information: We thank Taipei Medical University (NTUT-TMU-98-14) for their grant support. Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = aug,

doi = "10.3390/ijerph191610142",

language = "English",

volume = "19",

journal = "International journal of environmental research and public health",

issn = "1661-7827",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "16",

}

TY - JOUR

T1 - Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

AU - Hsu, Min Huei

AU - Hsu, Chia An

AU - Lai, Shih Chung

AU - Yen, Ju Chuan

PY - 2022/8

Y1 - 2022/8

N2 - The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.

AB - The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.

KW - age-related macular degeneration

KW - gout

KW - Taiwan National Health Insurance Research Database

UR - http://www.scopus.com/inward/record.url?scp=85136811104&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85136811104&partnerID=8YFLogxK

U2 - 10.3390/ijerph191610142

DO - 10.3390/ijerph191610142

M3 - Article

C2 - 36011777

AN - SCOPUS:85136811104

SN - 1661-7827

VL - 19

JO - International journal of environmental research and public health

JF - International journal of environmental research and public health

IS - 16

M1 - 10142

ER -

Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this