TY - JOUR
T1 - Gold-Based Nanostructures for Antibacterial Application
AU - Mutalik, Chinmaya
AU - Saukani, Muhammad
AU - Khafid, Muhamad
AU - Krisnawati, Dyah Ika
AU - Widodo,
AU - Darmayanti, Rofik
AU - Puspitasari, Betristasia
AU - Cheng, Tsai Mu
AU - Kuo, Tsung Rong
N1 - Funding Information:
We thank the financial support from the National Science and Technology Council (Taiwan, MOST 111-2113-M-038-003) and Taipei Medical University.
Publisher Copyright:
© 2023 by the authors.
PY - 2023/6
Y1 - 2023/6
N2 - Bacterial infections have become a fatal threat because of the abuse of antibiotics in the world. Various gold (Au)-based nanostructures have been extensively explored as antibacterial agents to combat bacterial infections based on their remarkable chemical and physical characteristics. Many Au-based nanostructures have been designed and their antibacterial activities and mechanisms have been further examined and demonstrated. In this review, we collected and summarized current developments of antibacterial agents of Au-based nanostructures, including Au nanoparticles (AuNPs), Au nanoclusters (AuNCs), Au nanorods (AuNRs), Au nanobipyramids (AuNBPs), and Au nanostars (AuNSs) according to their shapes, sizes, and surface modifications. The rational designs and antibacterial mechanisms of these Au-based nanostructures are further discussed. With the developments of Au-based nanostructures as novel antibacterial agents, we also provide perspectives, challenges, and opportunities for future practical clinical applications.
AB - Bacterial infections have become a fatal threat because of the abuse of antibiotics in the world. Various gold (Au)-based nanostructures have been extensively explored as antibacterial agents to combat bacterial infections based on their remarkable chemical and physical characteristics. Many Au-based nanostructures have been designed and their antibacterial activities and mechanisms have been further examined and demonstrated. In this review, we collected and summarized current developments of antibacterial agents of Au-based nanostructures, including Au nanoparticles (AuNPs), Au nanoclusters (AuNCs), Au nanorods (AuNRs), Au nanobipyramids (AuNBPs), and Au nanostars (AuNSs) according to their shapes, sizes, and surface modifications. The rational designs and antibacterial mechanisms of these Au-based nanostructures are further discussed. With the developments of Au-based nanostructures as novel antibacterial agents, we also provide perspectives, challenges, and opportunities for future practical clinical applications.
KW - antibacterial mechanism
KW - bacterial infection
KW - gold nanobipyramids
KW - gold nanoclusters
KW - gold nanoparticles
KW - gold nanorods
KW - gold nanostars
UR - http://www.scopus.com/inward/record.url?scp=85163993538&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85163993538&partnerID=8YFLogxK
U2 - 10.3390/ijms241210006
DO - 10.3390/ijms241210006
M3 - Review article
C2 - 37373154
AN - SCOPUS:85163993538
SN - 1661-6596
VL - 24
JO - International journal of molecular sciences
JF - International journal of molecular sciences
IS - 12
M1 - 10006
ER -