Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan

Ruwen Jou; Huang Yau Chen; Chen Yuan Chiang; Ming Chih Yu; Ih Jen Su

doi:10.1128/JCM.43.3.1390-1394.2005

Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan

Ruwen Jou
, Huang Yau Chen
, Chen Yuan Chiang
, Ming Chih Yu
, Ih Jen Su

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Of 162 multidrug-resistant Mycobacterium tuberculosis isolates from Taiwan, 60.5% were found to belong to the Beijing family on the basis of spoligotyping results. IS6110 restriction fragment length polymorphism fingerprinting showed genetic diversity among the multidrug-resistant isolates. Furthermore, 90.1% of the multidrug-resistant isolates had mutations in the rpoB gene, and 11 novel alleles were recognized.

Original language	English
Pages (from-to)	1390-1394
Number of pages	5
Journal	Journal of Clinical Microbiology
Volume	43
Issue number	3
DOIs	https://doi.org/10.1128/JCM.43.3.1390-1394.2005
Publication status	Published - Mar 2005

ASJC Scopus subject areas

Microbiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/JCM.43.3.1390-1394.2005

Cite this

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title = "Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan",

abstract = "Of 162 multidrug-resistant Mycobacterium tuberculosis isolates from Taiwan, 60.5\% were found to belong to the Beijing family on the basis of spoligotyping results. IS6110 restriction fragment length polymorphism fingerprinting showed genetic diversity among the multidrug-resistant isolates. Furthermore, 90.1\% of the multidrug-resistant isolates had mutations in the rpoB gene, and 11 novel alleles were recognized.",

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AU - Yu, Ming Chih

AU - Su, Ih Jen

PY - 2005/3

Y1 - 2005/3

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AB - Of 162 multidrug-resistant Mycobacterium tuberculosis isolates from Taiwan, 60.5% were found to belong to the Beijing family on the basis of spoligotyping results. IS6110 restriction fragment length polymorphism fingerprinting showed genetic diversity among the multidrug-resistant isolates. Furthermore, 90.1% of the multidrug-resistant isolates had mutations in the rpoB gene, and 11 novel alleles were recognized.

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Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan

Abstract

ASJC Scopus subject areas

UN SDGs

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