Gastrointestinal stromal tumor of the prostate: a case report and literature review

Chii Hong Lee; Yun Ho Lin; Hsiao Yu Lin; Chi Ming Lee; Jan Show Chu

doi:10.1016/j.humpath.2006.06.028

Gastrointestinal stromal tumor of the prostate: a case report and literature review

Chii Hong Lee, Yun Ho Lin, Hsiao Yu Lin, Chi Ming Lee, Jan Show Chu

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46 Citations (Scopus)

Abstract

We report a case of gastrointestinal stromal tumor (GIST) of the prostate in a 75-year-old man with dysuria and urinary retention. Digital rectal examination revealed a markedly enlarged prostate. The serum level of prostate-specific antigen was 0.2 ng/dL. Imaging studies showed an expanded prostate, measuring 6.7 × 5.6 × 5.5 cm, with heterogeneity in contrast enhancement. No metastatic disease was found. The pathologic diagnosis of prostatic GIST was made based on characteristic morphological features, immunoprofiles, and molecular analysis. The possibility of secondary involvement by a rectal GIST was excluded by radiological and intraoperative findings. To our knowledge, this is the second case of a primary GIST of the prostate reported in the literature.

Original language	English
Pages (from-to)	1361-1365
Number of pages	5
Journal	Human Pathology
Volume	37
Issue number	10
DOIs	https://doi.org/10.1016/j.humpath.2006.06.028
Publication status	Published - Oct 2006

Keywords

GIST
KIT
Prostate
Sarcoma

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.humpath.2006.06.028

Cite this

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title = "Gastrointestinal stromal tumor of the prostate: a case report and literature review",

abstract = "We report a case of gastrointestinal stromal tumor (GIST) of the prostate in a 75-year-old man with dysuria and urinary retention. Digital rectal examination revealed a markedly enlarged prostate. The serum level of prostate-specific antigen was 0.2 ng/dL. Imaging studies showed an expanded prostate, measuring 6.7 × 5.6 × 5.5 cm, with heterogeneity in contrast enhancement. No metastatic disease was found. The pathologic diagnosis of prostatic GIST was made based on characteristic morphological features, immunoprofiles, and molecular analysis. The possibility of secondary involvement by a rectal GIST was excluded by radiological and intraoperative findings. To our knowledge, this is the second case of a primary GIST of the prostate reported in the literature.",

keywords = "GIST, KIT, Prostate, Sarcoma",

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T2 - a case report and literature review

AU - Lee, Chii Hong

AU - Lin, Yun Ho

AU - Lin, Hsiao Yu

AU - Lee, Chi Ming

AU - Chu, Jan Show

PY - 2006/10

Y1 - 2006/10

N2 - We report a case of gastrointestinal stromal tumor (GIST) of the prostate in a 75-year-old man with dysuria and urinary retention. Digital rectal examination revealed a markedly enlarged prostate. The serum level of prostate-specific antigen was 0.2 ng/dL. Imaging studies showed an expanded prostate, measuring 6.7 × 5.6 × 5.5 cm, with heterogeneity in contrast enhancement. No metastatic disease was found. The pathologic diagnosis of prostatic GIST was made based on characteristic morphological features, immunoprofiles, and molecular analysis. The possibility of secondary involvement by a rectal GIST was excluded by radiological and intraoperative findings. To our knowledge, this is the second case of a primary GIST of the prostate reported in the literature.

AB - We report a case of gastrointestinal stromal tumor (GIST) of the prostate in a 75-year-old man with dysuria and urinary retention. Digital rectal examination revealed a markedly enlarged prostate. The serum level of prostate-specific antigen was 0.2 ng/dL. Imaging studies showed an expanded prostate, measuring 6.7 × 5.6 × 5.5 cm, with heterogeneity in contrast enhancement. No metastatic disease was found. The pathologic diagnosis of prostatic GIST was made based on characteristic morphological features, immunoprofiles, and molecular analysis. The possibility of secondary involvement by a rectal GIST was excluded by radiological and intraoperative findings. To our knowledge, this is the second case of a primary GIST of the prostate reported in the literature.

KW - GIST

KW - KIT

KW - Prostate

KW - Sarcoma

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Gastrointestinal stromal tumor of the prostate: a case report and literature review

Abstract

Keywords

ASJC Scopus subject areas

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