Abstract
There were more than 90% of systemic sclerosis (SSc) patients developing gastrointestinal tract involvement with affecting esophagus mostly. However, a typical gastrointestinal manifestation may be not the only result of SSc. We described a 70-year-old female with SSc presented poor appetite, intermittent heartburn sensation, nausea, frequent sensation of abdominal fullness, and intermittent dull pain for 2 months. The esophagogastroduodenoscopy showed gastrointestinal as gastroesophageal reflux disease. The biopsy revealed amorphous material deposited in the vascular walls and apple-green birefringence in a polarization examination with Congo red staining which proved amyloidosis. The SSc patient with gastrointestinal involvement suggests to receive esophagogastroduodenoscopy, and a biopsy may be helpful to these patients to examine the possibility of secondary amyloidosis. These patients need more aggressively disease activity control.
Original language | English |
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Pages (from-to) | 117-119 |
Number of pages | 3 |
Journal | Journal of Medical Sciences (Taiwan) |
Volume | 37 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jan 1 2017 |
Externally published | Yes |
Keywords
- Amyloidosis
- Gastroesophageal reflux disease
- Systemic sclerosis
ASJC Scopus subject areas
- Medicine(all)