Gallstone disease and the risk of stroke: A nationwide population-based study

Cheng Yu Wei; Tieh Chi Chung; Chien Hua Chen; Che Chen Lin; Fung Chang Sung; Wen Ting Chung; Woon Man Kung; Chung Y. Hsu; Yung Hsiang Yeh

doi:10.1016/j.jstrokecerebrovasdis.2014.04.024

Gallstone disease and the risk of stroke: A nationwide population-based study

Cheng Yu Wei
, Tieh Chi Chung
, Chien Hua Chen
, Che Chen Lin
, Fung Chang Sung
, Wen Ting Chung
, Woon Man Kung
, Chung Y. Hsu
, Yung Hsiang Yeh

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Background Gallstone disease (GD) and stroke share a number of risk factors including diabetes and hyperlipidemia. This nationwide population-based study was designed to estimate the risk of stroke after a diagnosis of GD. Methods Data were obtained from the Taiwan National Health Insurance Research Database. A total of 135,512 patients with a diagnosis of GD and 271,024 age- and gender-matched non-GD control patients were included to assess the risk of stroke using Cox proportional hazard regression. Results During the study period (2000-2003), 12,234 (153.67/10,000 person-years) strokes occurred among the GD patients, and 20,680 (114.83/10,000 person-years) among the controls. The diagnosis of GD carried a higher risk of developing ischemic and hemorrhagic stroke, with a hazard ratio (HR) of 1.28 and 1.33 (95% confidence interval [CI], 1.25-1.31 and 1.25-1.41, both P

Original language	English
Pages (from-to)	1813-1820
Number of pages	8
Journal	Journal of Stroke and Cerebrovascular Diseases
Volume	23
Issue number	7
DOIs	https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.04.024
Publication status	Published - 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cholelithiasis
epidemiology
gallstone disease
risk factors
Stroke

ASJC Scopus subject areas

Clinical Neurology
Surgery
Rehabilitation
Cardiology and Cardiovascular Medicine
General Medicine

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10.1016/j.jstrokecerebrovasdis.2014.04.024

Cite this

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title = "Gallstone disease and the risk of stroke: A nationwide population-based study",

abstract = "Background Gallstone disease (GD) and stroke share a number of risk factors including diabetes and hyperlipidemia. This nationwide population-based study was designed to estimate the risk of stroke after a diagnosis of GD. Methods Data were obtained from the Taiwan National Health Insurance Research Database. A total of 135,512 patients with a diagnosis of GD and 271,024 age- and gender-matched non-GD control patients were included to assess the risk of stroke using Cox proportional hazard regression. Results During the study period (2000-2003), 12,234 (153.67/10,000 person-years) strokes occurred among the GD patients, and 20,680 (114.83/10,000 person-years) among the controls. The diagnosis of GD carried a higher risk of developing ischemic and hemorrhagic stroke, with a hazard ratio (HR) of 1.28 and 1.33 (95\% confidence interval [CI], 1.25-1.31 and 1.25-1.41, both P ",

keywords = "cholelithiasis, epidemiology, gallstone disease, risk factors, Stroke",

author = "Wei, \{Cheng Yu\} and Chung, \{Tieh Chi\} and Chen, \{Chien Hua\} and Lin, \{Che Chen\} and Sung, \{Fung Chang\} and Chung, \{Wen Ting\} and Kung, \{Woon Man\} and Hsu, \{Chung Y.\} and Yeh, \{Yung Hsiang\}",

year = "2014",

doi = "10.1016/j.jstrokecerebrovasdis.2014.04.024",

language = "English",

volume = "23",

pages = "1813--1820",

journal = "Journal of Stroke and Cerebrovascular Diseases",

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T1 - Gallstone disease and the risk of stroke

T2 - A nationwide population-based study

AU - Wei, Cheng Yu

AU - Chung, Tieh Chi

AU - Chen, Chien Hua

AU - Lin, Che Chen

AU - Sung, Fung Chang

AU - Chung, Wen Ting

AU - Kung, Woon Man

AU - Hsu, Chung Y.

AU - Yeh, Yung Hsiang

PY - 2014

Y1 - 2014

N2 - Background Gallstone disease (GD) and stroke share a number of risk factors including diabetes and hyperlipidemia. This nationwide population-based study was designed to estimate the risk of stroke after a diagnosis of GD. Methods Data were obtained from the Taiwan National Health Insurance Research Database. A total of 135,512 patients with a diagnosis of GD and 271,024 age- and gender-matched non-GD control patients were included to assess the risk of stroke using Cox proportional hazard regression. Results During the study period (2000-2003), 12,234 (153.67/10,000 person-years) strokes occurred among the GD patients, and 20,680 (114.83/10,000 person-years) among the controls. The diagnosis of GD carried a higher risk of developing ischemic and hemorrhagic stroke, with a hazard ratio (HR) of 1.28 and 1.33 (95% confidence interval [CI], 1.25-1.31 and 1.25-1.41, both P

AB - Background Gallstone disease (GD) and stroke share a number of risk factors including diabetes and hyperlipidemia. This nationwide population-based study was designed to estimate the risk of stroke after a diagnosis of GD. Methods Data were obtained from the Taiwan National Health Insurance Research Database. A total of 135,512 patients with a diagnosis of GD and 271,024 age- and gender-matched non-GD control patients were included to assess the risk of stroke using Cox proportional hazard regression. Results During the study period (2000-2003), 12,234 (153.67/10,000 person-years) strokes occurred among the GD patients, and 20,680 (114.83/10,000 person-years) among the controls. The diagnosis of GD carried a higher risk of developing ischemic and hemorrhagic stroke, with a hazard ratio (HR) of 1.28 and 1.33 (95% confidence interval [CI], 1.25-1.31 and 1.25-1.41, both P

KW - cholelithiasis

KW - epidemiology

KW - gallstone disease

KW - risk factors

KW - Stroke

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SN - 1052-3057

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Gallstone disease and the risk of stroke: A nationwide population-based study

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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