Frequency stabilization using infinite impulse response filtering for SSFP fMRI at 3T

Ming Long Wu, Pei Hsin Wu, Teng Yi Huang, Yi Yu Shih, Ming Chung Chou, Hua Shan Liu, Hsiao Wen Chung, Cheng Yu Chen

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


The steady-state free precession (SSFP) method has been shown to exhibit strong potential for distortion-free functional magnetic resonance imaging (fMRI). One major challenge of SSFP fMRI is that the frequency band corresponding to the highest functional sensitivity is extremely narrow, leading to substantial loss of functional contrast in the presence of magnetic field drifts. In this study we propose a frequency stabilization scheme whereby an RF pulse with small flip angle is applied before each image scan, and the initial phase of the free induction decay (FID) signals is extracted to reflect temporal field drifts. A simple infinite impulse response (IIR) filter is further employed to obtain a low-pass-filtered estimate of the central reference frequency for the upcoming scan. Experimental results suggest that the proposed scheme can stabilize the frequency settings in accordance with field drifts, with oscillation amplitudes of

Original languageEnglish
Pages (from-to)369-379
Number of pages11
JournalMagnetic Resonance in Medicine
Issue number2
Publication statusPublished - Feb 2007
Externally publishedYes


  • Balanced steady-state free precession
  • Blood oxygenation-sensitive steady state
  • Frequency stabilization
  • Functional magnetic resonance imaging
  • IIR filter

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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