Flavanone and diphenylpropane glycosides and glycosidic acyl esters from viscum articulatum

Yu Jen Kuo; Yu Ching Yang; Li Jie Zhang; Ming Der Wu; Li Ming Yang Kuo; Yuh Chi Kuo; Syh Yuan Hwang; Cheng Jen Chou; Kuo Hsiung Lee; Hsiu O. Ho; Yao Haur Kuo

doi:10.1021/np9004294

Flavanone and diphenylpropane glycosides and glycosidic acyl esters from viscum articulatum

Yu Jen Kuo, Yu Ching Yang, Li Jie Zhang, Ming Der Wu, Li Ming Yang Kuo, Yuh Chi Kuo, Syh Yuan Hwang, Cheng Jen Chou, Kuo Hsiung Lee, Hsiu O. Ho, Yao Haur Kuo

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3"-tetramethoxy-l,3- diphenylpropane)4"-O-/β-D-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.

Original language	English
Pages (from-to)	109-114
Number of pages	6
Journal	Journal of Natural Products
Volume	73
Issue number	2
DOIs	https://doi.org/10.1021/np9004294
Publication status	Published - Feb 26 2010

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "Flavanone and diphenylpropane glycosides and glycosidic acyl esters from viscum articulatum",

abstract = "Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3{"}-tetramethoxy-l,3- diphenylpropane)4{"}-O-/β-D-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.",

author = "Kuo, {Yu Jen} and Yang, {Yu Ching} and Zhang, {Li Jie} and Wu, {Ming Der} and Kuo, {Li Ming Yang} and Kuo, {Yuh Chi} and Hwang, {Syh Yuan} and Chou, {Cheng Jen} and Lee, {Kuo Hsiung} and Ho, {Hsiu O.} and Kuo, {Yao Haur}",

year = "2010",

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doi = "10.1021/np9004294",

language = "English",

volume = "73",

pages = "109--114",

journal = "Journal of Natural Products",

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publisher = "American Chemical Society",

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T1 - Flavanone and diphenylpropane glycosides and glycosidic acyl esters from viscum articulatum

AU - Kuo, Yu Jen

AU - Yang, Yu Ching

AU - Zhang, Li Jie

AU - Wu, Ming Der

AU - Kuo, Li Ming Yang

AU - Kuo, Yuh Chi

AU - Hwang, Syh Yuan

AU - Chou, Cheng Jen

AU - Lee, Kuo Hsiung

AU - Ho, Hsiu O.

AU - Kuo, Yao Haur

PY - 2010/2/26

Y1 - 2010/2/26

N2 - Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3"-tetramethoxy-l,3- diphenylpropane)4"-O-/β-D-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.

AB - Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3"-tetramethoxy-l,3- diphenylpropane)4"-O-/β-D-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.

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Flavanone and diphenylpropane glycosides and glycosidic acyl esters from viscum articulatum

Abstract

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