Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties

Yung Chin Yang; Chien Chung Chen; Jhong Bo Wang; Yen Ching Wang; Feng Huei Lin

doi:10.1016/j.ceramint.2017.05.318

Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties

Yung Chin Yang, Chien Chung Chen, Jhong Bo Wang, Yen Ching Wang, Feng Huei Lin

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn₂(PO₄)₂ when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

Original language	English
Pages (from-to)	S829-S835
Journal	Ceramics International
Volume	43
DOIs	https://doi.org/10.1016/j.ceramint.2017.05.318
Publication status	Published - Aug 2017

Keywords

A: Powders: chemical preparation
D: Apatite
E: Biomedical applications

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Process Chemistry and Technology
Surfaces, Coatings and Films
Materials Chemistry

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10.1016/j.ceramint.2017.05.318

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title = "Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties",

abstract = "Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.",

keywords = "A: Powders: chemical preparation, D: Apatite, E: Biomedical applications",

author = "Yang, {Yung Chin} and Chen, {Chien Chung} and Wang, {Jhong Bo} and Wang, {Yen Ching} and Lin, {Feng Huei}",

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year = "2017",

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doi = "10.1016/j.ceramint.2017.05.318",

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T1 - Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties

AU - Yang, Yung Chin

AU - Chen, Chien Chung

AU - Wang, Jhong Bo

AU - Wang, Yen Ching

AU - Lin, Feng Huei

PY - 2017/8

Y1 - 2017/8

N2 - Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

AB - Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

KW - A: Powders: chemical preparation

KW - D: Apatite

KW - E: Biomedical applications

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JO - Ceramics International

JF - Ceramics International

ER -

Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties

Abstract

Keywords

ASJC Scopus subject areas

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