William H. Schuette, David E. Lees, Joan M. Bull, Harold Tipton, Duk Dim Young Duk Dim, Jacqueline Whang-Peng, Rose Smith, Gaither Bynum

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The use of whole body hyperthermia as an adjuvant mode of therapy for metastatic cancer requires an accurate control of core temperature so that the high temperature encountered during treatment may be employed safely. An electrically isolated system has been developed employing a programmable calculator to digitally control a motorized mixing valve regulating water temperature in a set of Hyper-Hypothermia blankets. The water temperature is regulated by feedback control employing patient esophageal temperature as a reference. The system uses a forced air heat exchanger with a reservoir as the source of cold water for cooling the patient once the control temperature has been reached. Whole body hyperthermia is currently being used on a routine basis at the National Institutes of Health, where patient core temperatures have been maintained at 41. 8C plus or minus 0. 1C for up to four hours.

Original languageEnglish
Pages (from-to)109-111
Number of pages3
Journal[No source information available]
Publication statusPublished - Dec 1 1978
Externally publishedYes

ASJC Scopus subject areas

  • General Engineering


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