Fat and Water Separation in Balanced Steady-State Free Precession Using the Dixon Method

Teng Yi Huang, Hsiao Wen Chung, Fu Nien Wang, Cheng Wen Ko, Cheng Yu Chen

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)


In this work the feasibility of separating fat and water signals using the balanced steady-state free precession (SSFP) technique is demonstrated. The technique is based on the observation (Scheffler and Hennig, Magnetic Resonance in Medicine 2003;49:395-397) that at the nominal values of TE = TR/2 in SSFP imaging, phase coherence can be achieved at essentially only two orientations (0° and 180°) relative to the RF pulses in the rotating frame, under the assumption of TR ≪ T2, and independently of the SSFP angle. This property allows in-phase and out-of-phase SSFP images to be obtained by proper choices of the center frequency offset, and thus allows the Dixon subtraction method to be utilized for effective fat-water separation. The TR and frequency offset for optimal fat-water separation are derived from theories. Experimental results from healthy subjects, using a 3.0 Tesla system, show that nearly complete fat suppression can be accomplished.

Original languageEnglish
Pages (from-to)243-247
Number of pages5
JournalMagnetic Resonance in Medicine
Issue number2
Publication statusPublished - Feb 2004
Externally publishedYes


  • Dixon method
  • Fat-water separation
  • Frequency offset
  • In-phase and out-of-phase images
  • Steady-state free precession

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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