@article{a92e69f241d24398956339e3df9c8dce,
title = "Facial telangiectasia - An unusual complication of neonatal lupus erythematosus: Report of one case",
abstract = "Neonatal lupus erythematosus (NLE) is an uncommon passive autoimmune disease caused by transplacental passage of anti-Ro/SSA and/or anti-La/SSB or anti-U1RNP maternal autoantibodies. Common clinical manifestations include cutaneous lupus lesions, cardiac disease, notably congenital heart block, hematologic abnormalities, and hepatobiliary disease. The cutaneous lesions of NLE are usually transient, disappearing about six months after birth when maternal antibodies disappear from the infant's circulation. Persistent telangiectasia is a rare complication of NLE. We report a 3-year-old female who had cutaneous lupus with persistent facial telangiectasias over the frontal area. She was diagnosed with NLE at 2 months of age. Her findings then included cutaneous lupus, hemolytic anemia, a high titer of antinuclear antibodies (1:640) with a speckled pattern, positive anti-Ro/SSA and anti-La/SSB antibodies, and absence of anti-dsDNA antibodies. Her mother had systemic lupus erythematosus with the presence of high titer of antinuclear antibodies (1:1260) with a speckled pattern and positive anti-Ro/SSA and anti-La/SSB antibodies. The child's cutaneous lupus and hemolytic anemia disappeared at 6 months of age, but the telangiectasia persisted.",
keywords = "Hemolytic anemia, Neonatal lupus erythematosus, Telangiectasia, antinuclear antibody, corticosteroid, double stranded DNA, double stranded DNA antibody, La antibody, maternal antibody, Ro antibody, small nuclear ribonucleoprotein, unclassified drug, antibody titer, article, autoimmune disease, case report, clinical feature, congenital heart block, facial telangiectasia, female, fetomaternal transfusion, heart disease, hematologic disease, hemolytic anemia, hepatobiliary disease, human, human tissue, lupus erythematosus, newborn disease, newborn lupus erythematosus, preschool child, rare disease, skin lupus erythematosus, systemic lupus erythematosus, telangiectasia, Antibodies, Antinuclear, Diagnosis, Differential, Face, Family Health, Female, Humans, Infant, Lupus Erythematosus, Cutaneous, Telangiectasis",
author = "Sheng-Chieh Lin and Shyh-Dar Shyur and Jiunn-Yi Wu and Li-Hsin Huang and Yi-Chun Ma",
note = "被引用次數：3 Export Date: 7 April 2016 CODEN: TEYZF 通訊地址: Shyur, S.-D.; Department of Pediatrics, Mackay Memorial Hospital, No. 92, Chung-Shan N. Road, Taipei 104, Taiwan 化學物質/CAS: Antibodies, Antinuclear 參考文獻: Dorner, T., Feist, E., Pruss, A., Chaoui, R., Goldner, B., Hiepe, F., Significance of autoantibodies in neonatal lupus erythematosus (2000) Int Arch Allergy Immunol, 123, pp. 58-66; McCuistion, C.H., Schoch, E.P., Possible discoid lupus erythematosus in a newborn infant (1954) Arch Dermatol, 70, pp. 782-785; Le Thi Houng, D., Wechsler, B., Piette, J.C., Bletry, O., Godean, P., Pregnancy and its outcome in systemic lupus erythematosus (1994) Q J Med, 87, pp. 721-729; Silverman, E.D., Laxer, R.M., Neonatal lupus erythematosus (1997) Rheum Dis Clin North Am, 23, pp. 599-618; Vonderheid, E.C., Koblenzer, P.J., Ming, P.M., Neonatal lupus erythematosus: Report of four cases with review of the literature (1976) Arch Dermatol, 112, pp. 698-705; Bourke, J.F., Burns, D.A., Neonatal lupus erythematosus with persistent telangiectasia and spastic paraparesis (1993) Clin Exp Dermatol, 18, pp. 271-273; Cortran, R.S., Kumar, V., Robbins, S.L., (1989) Robbins' Pathologic Basis of Disease, 4th Ed., p. 590. , Philadelphia: WB Saunders; Thornton, C.M., Eichenfield, L.F., Shinall, E.A., Cutaneous telangiectases in neonatal lupus erythematosus (1995) J Am Acad Dermatol, 33, pp. 19-25; Neiman, A.R., Lee, L.A., Weston, W.L., Buyon, J.P., Cutaneous manifestations of neonatal lupus without heart block: Characteristics of mothers and children enrolled in a national registry (2000) J Pediatr, 137, pp. 674-680; Burch, J.M., Lee, L.A., Weston, W.L., Neonatal lupus erythematosus (2002) Dermatol Nur, 14, pp. 157-160; Carrascosa, J.M., Ribera, M., Bielsa, I., Coroleu, W., Ferrandiz, C., Cutis marmorata telangiectatica congenita or neonatal lupus? (1996) Pediatr Dermatol, 13, pp. 230-232; Prendiville, J.S., Cabral, D.A., Poskitt, J., Sargent, M.A., Central nervous system involvement in neonatal lupus erythematosus (2003) Pediatr Dermatol, 20, pp. 60-67; Goldman, M.P., Weiss, R.A., Brody, H.J., Treatment of facial telangiectasia with sclerotherapy, laser surgery, and/or electrodessication: A review (1993) J Dermatol Surg Oncol, 19, pp. 899-906; Buyon, J.P., Hiebert, R., Copel, J., Autoimmune-associated congenital heart block: Demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry (1998) J Am Coll Cardiol, 31, pp. 1658-1666",
year = "2004",
language = "English",
volume = "45",
pages = "246--248",
journal = "Acta Paediatrica Taiwanica",
issn = "1608-8115",
publisher = "臺灣兒科醫學會",
number = "4",
}
