Extravascular lung water correlates multiorgan dysfunction syndrome and mortality in sepsis

Fu Tsai Chung; Horng Chyuan Lin; Chih Hsi Kuo; Chih Teng Yu; Chun Liang Chou; Kang Yun Lee; Han Pin Kuo; Shu Min Lin

doi:10.1371/journal.pone.0015265

Extravascular lung water correlates multiorgan dysfunction syndrome and mortality in sepsis

Fu Tsai Chung, Horng Chyuan Lin, Chih Hsi Kuo, Chih Teng Yu, Chun Liang Chou, Kang Yun Lee, Han Pin Kuo, Shu Min Lin

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Abstract

Background: This study was designated to investigate whether increased extravascular lung water index (EVLWI) may correlate multiple organ dysfunction syndrome (MODS) and mortality in sepsis. Methods: We designed a prospective cohort study in an intensive care unit of a tertiary care hospital. Sixty-seven patients with severe sepsis were included. Data were used to determine an association between EVLWI and the development of MODS and mortality. These connections were determined by the multiple logistic regression, plotting the receiver operating characteristic (ROC) curve and by Spearman test. Results: EVLWI levels were higher in MODS patients on day 1 (median (IQR), 18(12.8-23.9) ml/kg, n = 38, p

Original language	English
Article number	e15265
Journal	PLoS ONE
Volume	5
Issue number	12
DOIs	https://doi.org/10.1371/journal.pone.0015265
Publication status	Published - 2010
Externally published	Yes

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title = "Extravascular lung water correlates multiorgan dysfunction syndrome and mortality in sepsis",

abstract = "Background: This study was designated to investigate whether increased extravascular lung water index (EVLWI) may correlate multiple organ dysfunction syndrome (MODS) and mortality in sepsis. Methods: We designed a prospective cohort study in an intensive care unit of a tertiary care hospital. Sixty-seven patients with severe sepsis were included. Data were used to determine an association between EVLWI and the development of MODS and mortality. These connections were determined by the multiple logistic regression, plotting the receiver operating characteristic (ROC) curve and by Spearman test. Results: EVLWI levels were higher in MODS patients on day 1 (median (IQR), 18(12.8-23.9) ml/kg, n = 38, p",

author = "Chung, {Fu Tsai} and Lin, {Horng Chyuan} and Kuo, {Chih Hsi} and Yu, {Chih Teng} and Chou, {Chun Liang} and Lee, {Kang Yun} and Kuo, {Han Pin} and Lin, {Shu Min}",

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T1 - Extravascular lung water correlates multiorgan dysfunction syndrome and mortality in sepsis

AU - Chung, Fu Tsai

AU - Lin, Horng Chyuan

AU - Kuo, Chih Hsi

AU - Yu, Chih Teng

AU - Chou, Chun Liang

AU - Lee, Kang Yun

AU - Kuo, Han Pin

AU - Lin, Shu Min

PY - 2010

Y1 - 2010

N2 - Background: This study was designated to investigate whether increased extravascular lung water index (EVLWI) may correlate multiple organ dysfunction syndrome (MODS) and mortality in sepsis. Methods: We designed a prospective cohort study in an intensive care unit of a tertiary care hospital. Sixty-seven patients with severe sepsis were included. Data were used to determine an association between EVLWI and the development of MODS and mortality. These connections were determined by the multiple logistic regression, plotting the receiver operating characteristic (ROC) curve and by Spearman test. Results: EVLWI levels were higher in MODS patients on day 1 (median (IQR), 18(12.8-23.9) ml/kg, n = 38, p

AB - Background: This study was designated to investigate whether increased extravascular lung water index (EVLWI) may correlate multiple organ dysfunction syndrome (MODS) and mortality in sepsis. Methods: We designed a prospective cohort study in an intensive care unit of a tertiary care hospital. Sixty-seven patients with severe sepsis were included. Data were used to determine an association between EVLWI and the development of MODS and mortality. These connections were determined by the multiple logistic regression, plotting the receiver operating characteristic (ROC) curve and by Spearman test. Results: EVLWI levels were higher in MODS patients on day 1 (median (IQR), 18(12.8-23.9) ml/kg, n = 38, p

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Extravascular lung water correlates multiorgan dysfunction syndrome and mortality in sepsis

Abstract

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