TY - JOUR
T1 - Evaluations of Antibacterial Properties of Zingiber purpureum Essential Oil Against 13 Different Gram-positive and Gram-negative Bacteria
AU - Tandirogang, Nataniel
AU - Anitasari, Silvia
AU - Arung, Enos Tangke
AU - Paramita, Swandari
AU - Shen, Yung Kang
N1 - Funding Information:
The Lembaga Pengelola Dana Pendidikan (LPDP) funded a part of this study through the RISPRO program (Grant No. 6/ F1/P-KCOVID-19.2B3/IX/2020). We'd also like to express our gratitude to Universitas Mulawarman for supporting research laboratories in conducting this study, and School of Dental Technology, College of Oral Medicine, Taipei Medical University for the collaboration.
Publisher Copyright:
© 2022, Indonesian Biomedical Journal. All Rights Reserved.
PY - 2022
Y1 - 2022
N2 - BACKGROUND: Indonesia's tropical forest is home to around 80% of the world's medicinal plants. One of these is Zingiber purpureum, which have traditionally been used to treat joint discomfort, the common cold, and jaundice. The rhizomes of this plant have been suggested to possess antibacterial action in the treatment of infections. In this study, Z. purpureum was screened for antibacterial activity against 13 bacteria (Gram-positive and Gram-negative). METHODS: Z. purpureum rhizomes were obtained and the distillated extracts were made to generate essential oil. The minimum inhibitory concentration (MIC) and Kirby Bauer disk diffusion methods were used to determine the antibacterial activity. RESULTS: All bacteria activity were inhibited by the essential oil of Z. purpureum at concentrations ranging from 2.5 vol% to 10 vol%. However, several bacterias (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) were inhibited at the lowest concentration (0.63 vol %), with the inhibition zones ranging from 6.7 mm to 8.0 mm. Meanwhile, the widest inhibition zone (13.3 mm) was reported on E. cloacae at 10 vol% concentration. CONCLUSION: A 10 vol% Z. purpureum rhizome extract inhibits Gram-positive and Gram-negative bacteria, particularly those that are resistant to a variety of antibiotics.
AB - BACKGROUND: Indonesia's tropical forest is home to around 80% of the world's medicinal plants. One of these is Zingiber purpureum, which have traditionally been used to treat joint discomfort, the common cold, and jaundice. The rhizomes of this plant have been suggested to possess antibacterial action in the treatment of infections. In this study, Z. purpureum was screened for antibacterial activity against 13 bacteria (Gram-positive and Gram-negative). METHODS: Z. purpureum rhizomes were obtained and the distillated extracts were made to generate essential oil. The minimum inhibitory concentration (MIC) and Kirby Bauer disk diffusion methods were used to determine the antibacterial activity. RESULTS: All bacteria activity were inhibited by the essential oil of Z. purpureum at concentrations ranging from 2.5 vol% to 10 vol%. However, several bacterias (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) were inhibited at the lowest concentration (0.63 vol %), with the inhibition zones ranging from 6.7 mm to 8.0 mm. Meanwhile, the widest inhibition zone (13.3 mm) was reported on E. cloacae at 10 vol% concentration. CONCLUSION: A 10 vol% Z. purpureum rhizome extract inhibits Gram-positive and Gram-negative bacteria, particularly those that are resistant to a variety of antibiotics.
KW - Antibacterial agents
KW - Infection
KW - Susceptibility test
KW - Zingiber purpureum
UR - https://www.scopus.com/pages/publications/85138144777
UR - https://www.scopus.com/inward/citedby.url?scp=85138144777&partnerID=8YFLogxK
U2 - 10.18585/inabj.v14i3.1967
DO - 10.18585/inabj.v14i3.1967
M3 - Article
AN - SCOPUS:85138144777
SN - 2085-3297
VL - 14
SP - 303
EP - 308
JO - Indonesian Biomedical Journal
JF - Indonesian Biomedical Journal
IS - 3
ER -