Evaluation of equilibrium dialysis volume shifts: A comment

Stephen H. Curry, Oliver Y.P. Hu

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Previous authors have presented in this journal an equation defining the fractional shift in volume (fs)as a general equation implying applicability to a wide variety of circumstances. The equation concerned actually applies only when the starting volumes before dialysis are equal. A better general definition is given by fs=(volume shift)/(starting volume of protein solution).

Original languageEnglish
Pages (from-to)463-465
Number of pages3
JournalJournal of Pharmacokinetics and Biopharmaceutics
Issue number4
Publication statusPublished - Aug 1 1984
Externally publishedYes


  • equilibrium dialysis
  • protein binding
  • volume shift

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)


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