Abstract
Previous authors have presented in this journal an equation defining the fractional shift in volume (fs)as a general equation implying applicability to a wide variety of circumstances. The equation concerned actually applies only when the starting volumes before dialysis are equal. A better general definition is given by fs=(volume shift)/(starting volume of protein solution).
Original language | English |
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Pages (from-to) | 463-465 |
Number of pages | 3 |
Journal | Journal of Pharmacokinetics and Biopharmaceutics |
Volume | 12 |
Issue number | 4 |
DOIs | |
Publication status | Published - Aug 1 1984 |
Externally published | Yes |
Keywords
- equilibrium dialysis
- protein binding
- volume shift
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmacology (medical)