Etiology of community acquired pneumonia among adult patients requiring hospitalization in Taiwan

Tsai Ling Lauderdale, Feng Yee Chang, Ren Jy Ben, Hsiao Chuan Yin, Yuen Hua Ni, Jen Wen Tsai, Shu Hsing Cheng, Jann Tay Wang, Yung Ching Liu, Yan Wan Cheng, Shu Ting Chen, Chang Phone Fung, Yin Ching Chuang, Hsiao Pei Cheng, Daniel C T Lu, Chieh Ju Liu, I. Wen Huang, Che Lun Hung, Chin Fu Hsiao, Monto Ho

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)


Background: There has not been a comprehensive multi-center study investigating the microbial profile of community acquired pneumonia (CAP) in Taiwan. Methods: A prospective study of adult CAP patients requiring hospitalization between December 2001 and April 2002 was carried out in 13 hospitals in Taiwan. Etiology was determined based on laboratory data from blood and sputum cultures plus serology from paired serum and urine antigen detection tests. Results: Etiology was assigned to 99 (58.9%) of the 168 patients having the most complete data for etiology determination, with mixed infection in 21 (12.5%) patients. More than half (51.8%) of the patients were > 60 years and 63.7% of the patients were males. The most common etiologic agent was Streptococcus pneumoniae (40, 23.8%), the majority (60%, 24 cases) of which was detected by positive urine antigen test. Other common agents included Mycoplasma pneumoniae (24, 14.3%), Chlamydia pneumoniae (12, 7.1%), Influenza A virus (11, 6.5%), Klebsiella pneumoniae (8, 4.8%) and Haemophilus influenzae (8, 4.8%). The prevalence of S. pneumoniae and M. pneumoniae was highest in patients > 60 years (25/87, 28.7%), and

Original languageEnglish
Pages (from-to)1079-1086
Number of pages8
JournalRespiratory Medicine
Issue number9
Publication statusPublished - Sept 2005
Externally publishedYes


  • Cap in hospitalized adult patients
  • CAP in Taiwan
  • Community acquired pneumonia
  • Etiology of CAP

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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