Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999

Chung Guei Huang; Kuo Chien Tsao; Tzou Yien Lin; Yhu Chering Huang; Li Ang Lee; Tzu Hou Chen; Ya Ling Huang; Shin Ru Shih

doi:10.1007/s00705-010-0596-1

Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999

Chung Guei Huang, Kuo Chien Tsao, Tzou Yien Lin, Yhu Chering Huang, Li Ang Lee, Tzu Hou Chen, Ya Ling Huang, Shin Ru Shih

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Human metapneumovirus (hMPV) causes both upper and lower respiratory tract infection worldwide. Because little is known about the estimated level of exposure to hMPV in Taiwan, data for 1999 are presented. One thousand one hundred twenty sera from otherwise healthy community-based subjects aged 1 month to 99 years were tested in an enzyme-linked immunosorbent assay; the proportion of seropositive individuals was 68.1%. Moreover, 53.2% of preschool children were seronegative, whereas 88.3% of school-aged individuals and 93.7% of adults had antibodies to hMPV. In summary, the present study provides an earlier evidence of a high rate of exposure to hMPV characterized the seroprevalence among Taiwanese individuals in 1999. In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV.

Original language	English
Pages (from-to)	343-350
Number of pages	8
Journal	Archives of Virology
Volume	155
Issue number	3
DOIs	https://doi.org/10.1007/s00705-010-0596-1
Publication status	Published - Mar 2010
Externally published	Yes

ASJC Scopus subject areas

Virology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00705-010-0596-1

Cite this

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title = "Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999",

abstract = "Human metapneumovirus (hMPV) causes both upper and lower respiratory tract infection worldwide. Because little is known about the estimated level of exposure to hMPV in Taiwan, data for 1999 are presented. One thousand one hundred twenty sera from otherwise healthy community-based subjects aged 1 month to 99 years were tested in an enzyme-linked immunosorbent assay; the proportion of seropositive individuals was 68.1%. Moreover, 53.2% of preschool children were seronegative, whereas 88.3% of school-aged individuals and 93.7% of adults had antibodies to hMPV. In summary, the present study provides an earlier evidence of a high rate of exposure to hMPV characterized the seroprevalence among Taiwanese individuals in 1999. In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV.",

author = "Huang, {Chung Guei} and Tsao, {Kuo Chien} and Lin, {Tzou Yien} and Huang, {Yhu Chering} and Lee, {Li Ang} and Chen, {Tzu Hou} and Huang, {Ya Ling} and Shih, {Shin Ru}",

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doi = "10.1007/s00705-010-0596-1",

language = "English",

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pages = "343--350",

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T1 - Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999

AU - Huang, Chung Guei

AU - Tsao, Kuo Chien

AU - Lin, Tzou Yien

AU - Huang, Yhu Chering

AU - Lee, Li Ang

AU - Chen, Tzu Hou

AU - Huang, Ya Ling

AU - Shih, Shin Ru

PY - 2010/3

Y1 - 2010/3

N2 - Human metapneumovirus (hMPV) causes both upper and lower respiratory tract infection worldwide. Because little is known about the estimated level of exposure to hMPV in Taiwan, data for 1999 are presented. One thousand one hundred twenty sera from otherwise healthy community-based subjects aged 1 month to 99 years were tested in an enzyme-linked immunosorbent assay; the proportion of seropositive individuals was 68.1%. Moreover, 53.2% of preschool children were seronegative, whereas 88.3% of school-aged individuals and 93.7% of adults had antibodies to hMPV. In summary, the present study provides an earlier evidence of a high rate of exposure to hMPV characterized the seroprevalence among Taiwanese individuals in 1999. In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV.

AB - Human metapneumovirus (hMPV) causes both upper and lower respiratory tract infection worldwide. Because little is known about the estimated level of exposure to hMPV in Taiwan, data for 1999 are presented. One thousand one hundred twenty sera from otherwise healthy community-based subjects aged 1 month to 99 years were tested in an enzyme-linked immunosorbent assay; the proportion of seropositive individuals was 68.1%. Moreover, 53.2% of preschool children were seronegative, whereas 88.3% of school-aged individuals and 93.7% of adults had antibodies to hMPV. In summary, the present study provides an earlier evidence of a high rate of exposure to hMPV characterized the seroprevalence among Taiwanese individuals in 1999. In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV.

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Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999

Abstract

ASJC Scopus subject areas

UN SDGs

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