Erythropoietins from teleosts

C. Y. Chu; C. H. Cheng; C. H. Yang; C. J. Huang

doi:10.1007/s00018-008-8231-y

Erythropoietins from teleosts

C. Y. Chu, C. H. Cheng, C. H. Yang, C. J. Huang

Research output: Contribution to journal › Review article › peer-review

28 Citations (Scopus)

Abstract

The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.

Original language	English
Pages (from-to)	3545-3552
Number of pages	8
Journal	Cellular and Molecular Life Sciences
Volume	65
Issue number	22
DOIs	https://doi.org/10.1007/s00018-008-8231-y
Publication status	Published - Nov 2008
Externally published	Yes

Keywords

EPO
EPO receptor
Glycosylation
Secretion
Zebrafish

ASJC Scopus subject areas

Molecular Medicine
Molecular Biology
Pharmacology
Cellular and Molecular Neuroscience
Cell Biology

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10.1007/s00018-008-8231-y

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title = "Erythropoietins from teleosts",

abstract = "The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.",

keywords = "EPO, EPO receptor, Glycosylation, Secretion, Zebrafish",

author = "Chu, {C. Y.} and Cheng, {C. H.} and Yang, {C. H.} and Huang, {C. J.}",

year = "2008",

month = nov,

doi = "10.1007/s00018-008-8231-y",

language = "English",

volume = "65",

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journal = "Cellular and Molecular Life Sciences",

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T1 - Erythropoietins from teleosts

AU - Chu, C. Y.

AU - Cheng, C. H.

AU - Yang, C. H.

AU - Huang, C. J.

PY - 2008/11

Y1 - 2008/11

N2 - The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.

AB - The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.

KW - EPO

KW - EPO receptor

KW - Glycosylation

KW - Secretion

KW - Zebrafish

UR - http://www.scopus.com/inward/record.url?scp=56549104115&partnerID=8YFLogxK

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DO - 10.1007/s00018-008-8231-y

M3 - Review article

C2 - 18622577

AN - SCOPUS:56549104115

SN - 1420-682X

VL - 65

SP - 3545

EP - 3552

JO - Cellular and Molecular Life Sciences

JF - Cellular and Molecular Life Sciences

IS - 22

ER -

Erythropoietins from teleosts

Abstract

Keywords

ASJC Scopus subject areas

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