Epithelial origin of polyoma salivary tumors in mice: Evidence based on chromosome-marked cells

C. J. Dawe; J. Whang-Peng; W. D. Morgan; E. C. Hearon; T. Knutsen

doi:10.1126/science.171.3969.394

Epithelial origin of polyoma salivary tumors in mice: Evidence based on chromosome-marked cells

C. J. Dawe, J. Whang-Peng, W. D. Morgan, E. C. Hearon, T. Knutsen

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Trypsin dissection of epithelium from mesenchyme of salivary gland rudiments allows reassembly of glands having either epithelium or mesenchyme selectively marked by T₆ chromosomes. Virus-induced tumors in such glands invariably bear the karyotype of the epithelial component. The method solves a specific example from a group of classical problems concerning epithelial as opposed to mesenchymal origin of neoplasms.

Original language	English
Pages (from-to)	394-397
Number of pages	4
Journal	Science
Volume	171
Issue number	3969
DOIs	https://doi.org/10.1126/science.171.3969.394
Publication status	Published - Jan 1 1971
Externally published	Yes

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abstract = "Trypsin dissection of epithelium from mesenchyme of salivary gland rudiments allows reassembly of glands having either epithelium or mesenchyme selectively marked by T6 chromosomes. Virus-induced tumors in such glands invariably bear the karyotype of the epithelial component. The method solves a specific example from a group of classical problems concerning epithelial as opposed to mesenchymal origin of neoplasms.",

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AU - Hearon, E. C.

AU - Knutsen, T.

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Epithelial origin of polyoma salivary tumors in mice: Evidence based on chromosome-marked cells

Abstract

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