Epithelial maturation and extracellular matrix in reduced enamel epithelium

Mao Shung Huang, Bey Rong Guo, Cheng Chen Hsu, James Duen Jeng Wang, Borcherng Su

Research output: Contribution to journalArticlepeer-review


Objective: To evaluate epithelial-mesenchymal interactions in morphological homeostasis through histologically orientated observations on the reduced enamel in epithelium. Study Design: Specimens were taken from impacted molar sites in 20 patients using the surgery. These were processed using standard histological, pathological and biochemical techniques. Slides were observed with a Nikon Eclipse E-600, Plan Apo piece, Microscopy, and photography was done using a Nikon Coolpix 990 digital camera. Results: Radiolucent lesions displayed the supporting fibrous connective tissue wall with stratified squamous epithelium lining mostly. None of the specimens displayed prominent CAM 5.2, and anti-human K7 reactivity, and PAS positive staining. Conclusion: While the results of this study suggest that the reduced enamel epithelium showed a lower tendency in cell cycle, it does indicate that a histologically oriented study of reduced enamel epithelium is needed for the understanding of epithelial-mesenchymal interactions in morphogenesis.

Original languageEnglish
Pages (from-to)287-298
Number of pages12
JournalResearch Communications in Molecular Pathology and Pharmacology
Issue number5-6
Publication statusPublished - 2001


  • Enamel epithelium
  • Epithelial maturation
  • Epithelial-mesenchymal interactions
  • Extracellular matrix
  • Impacted molar sites

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology


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