TY - JOUR
T1 - Epidemiology and Prevalence of Bloodstream Infections in a Regional Hospital in Northern Taiwan During 2008-2013
AU - Hsieh, Wen Shyang
AU - Tsai, Yin Tai
AU - Chi, Wei Ming
AU - Wu, Hsueh Hsia
N1 - Publisher Copyright:
© 2014 Taipei Medical University.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28% of these sets, as follows: 5.48% exhibited growth of a single microorganism; 1.56% exhibited growth of more than one microorganism; and 3.24% exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02%); Enterobacteriaceae (56.51%); glucose nonfermentative Gram-negative bacteria (7.27%); yeast (6.22%); and anaerobic bacteria (6.64%). Most microorganisms were identified as follows: Escherichia coli (33.80%); Staphylococcus aureus (14.20%); Klebsiella pneumoniae (11.41%); Pseudomonas aeruginosa (3.17%); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68%). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.
AB - Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28% of these sets, as follows: 5.48% exhibited growth of a single microorganism; 1.56% exhibited growth of more than one microorganism; and 3.24% exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02%); Enterobacteriaceae (56.51%); glucose nonfermentative Gram-negative bacteria (7.27%); yeast (6.22%); and anaerobic bacteria (6.64%). Most microorganisms were identified as follows: Escherichia coli (33.80%); Staphylococcus aureus (14.20%); Klebsiella pneumoniae (11.41%); Pseudomonas aeruginosa (3.17%); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68%). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.
KW - Escherichia coli
KW - Group B Streptococcus
KW - Infant bacteremia
KW - Staphylococcus aureus
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U2 - 10.1016/j.jecm.2014.10.011
DO - 10.1016/j.jecm.2014.10.011
M3 - Article
AN - SCOPUS:84916209836
SN - 1878-3317
VL - 6
SP - 187
EP - 189
JO - Journal of Experimental and Clinical Medicine (Taiwan)
JF - Journal of Experimental and Clinical Medicine (Taiwan)
IS - 6
ER -