Abstract
The hydrothermal stability and oxidation activity of cytochrome c (cty c) by immobilization in the nanochannels of mesoporous aluminosilicates were discussed. The cytochrome c immobilized in MAS-9 undergo facile unfolding during hydrothermal stability. The stability and high catalytic activity of cyt c immobilized in mesoporous silicas were attributed to the electrostatic attraction between the pore surface and cyt c and the confinement provided by nanochannels. It was found that by increasing the concentration of the spin trapping agent, cyt c catalyzes a homolytic cleavage of the O-O bond of hydroperoxide and generates a protein cation radicals.
Original language | English |
---|---|
Pages (from-to) | 12277-12286 |
Number of pages | 10 |
Journal | Journal of Physical Chemistry B |
Volume | 109 |
Issue number | 25 |
DOIs | |
Publication status | Published - Jun 30 2005 |
Externally published | Yes |
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Surfaces, Coatings and Films
- Materials Chemistry