Enhancement of biocompatibility on bioactive Ti-Nb-based alloy by high-density plasma modification

En Yu Wu, Keng Liang Ou, Yung Ning Pan

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The formations and characteristics of oxides on the surfaces of the plasma-treated Ti-Nb-Hf alloys were investigated by employing X-ray photoelectron spectroscopy, X-ray powder diffractometer and scanning electron microscopy. Further, the non-treated and plasma-treated specimens were incubated in phosphate-buffered saline (PBS) containing albumin to evaluate their biocompatibility. The results indicate that through 02-plasma treatment, the thickness of the oxide layer increases, and the surface roughness improves, exhibiting little protuberances and numerous micropores and cavities on the treated surface. The compositions of the oxide layers in the specimen without O2-plasma treatment consist of TiO, Ti2O3 and TiO2, and the oxides transform to mainly TiO2 as the specimen is treated with O2-plasma. In addition, the formation of nitrides by allylamine plasma treatment can provide amino-group linkings for the attachment of albumin. Plasma oxidation and polymerization are believed to improve biocompatibility and therefore promote osseointegration.

Original languageEnglish
Pages (from-to)3164-3169
Number of pages6
JournalMaterials Transactions
Issue number12
Publication statusPublished - Dec 2007


  • Osseointegration
  • Oxidation, biocompatibility
  • Plasma treatment
  • Titanium-niobium-hafnium alloy

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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