TY - JOUR
T1 - Endoscopic injection of alcohol to stop peptic ulcer hemorrhage
T2 - Experience with 115 cases
AU - Lin, Hwai Jeng
AU - Lee, Fa Yauh
AU - Lee, Chen Hsen
AU - Lee, Shou Dong
PY - 1991/8
Y1 - 1991/8
N2 - In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.
AB - In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.
KW - Endoscopic injection
KW - Hemostasis
KW - Peptic ulcer hemorrhage
KW - Shock
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U2 - 10.1097/00004836-199108000-00003
DO - 10.1097/00004836-199108000-00003
M3 - Article
C2 - 1918841
AN - SCOPUS:0025787356
SN - 0192-0790
VL - 13
SP - 376
EP - 379
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
IS - 4
ER -