@article{d7885e2201874a57bbcb06314c00ee14,
title = "Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living formosan sambar deer (Rusa unicolor swinhoei)",
abstract = "We documented a case of a free-living Formosan sambar deer (Rusa unicolor swinhoei) infected with a newly discovered ruminant Rhadinovirus (RuRv). Non-purulent encephalitis was the primary histological lesion of the sambar deer. We conducted nested PCR to screen for herpesvirus using generic primers targeting the DNA polymerase gene. In addition, we found that DNA polymerase gene of the sambar deer RuRv was present in the macrophage distributed in the Virchow Robin space with histopathologic lesions by chromogenic in-situ hybridization (CISH). The phylogenetic analysis indicated a high similarity between the viral sequence isolated from fallow deer and our case. This result suggests the possibility of cross-species transmission from other exotic Cervidae reservoir to the Formosan sambar deer. {\textcopyright} 2018 The Japanese Society of Veterinary Science.",
keywords = "Cervidae, Formosan sambar deer, Ruminant rhadinovirus, animal, case report, cell line, classification, deer, herpes virus infection, isolation and purification, male, molecular typing, phylogeny, real time polymerase chain reaction, Rhadinovirus, veterinary medicine, virology, virus encephalitis, Animals, Cell Line, Deer, Encephalitis, Viral, Herpesviridae Infections, Male, Molecular Typing, Phylogeny, Real-Time Polymerase Chain Reaction, Cervidae, Formosan sambar deer, Ruminant rhadinovirus",
author = "A.-M. Chang and C.-C. Chen and C.-D. Chang and Y.-L. Huang and G.-M. Ke and B.A. Walther",
note = "Export Date: 12 October 2018 通訊地址: Chen, C.-C.; Institute of wildlife conservation, College of Veterinary Medicine, National Pingtung University of Science and Technology, 1, Shuefu Road, Taiwan; 電子郵件: ccchen@mail.npust.edu.tw 出資正文: ACKNOWLEDGMENTS. This study was supported by Yushan National Park, Construction and Planning Administration, Ministry 參考文獻: Baxter, S.I.F., Pow, I., Bridgen, A., Reid, H.W., PCR detection of the sheep-associated agent of malignant catarrhal fever (1993) Arch. Virol., 132, pp. 145-159; Ensser, A., Neipel, F., Fickenscher, H., Rhadinovirus pathogenesis (2002) Structure-Function Relationships of Human Pathogenic Viruses, pp. 349-429. , Holzenburg, A. and Bogner, EKluwer Academic Publishers, New York; (2014) Schedule of Protected Wildlife, , http://www.conservation.forest.gov.tw, Forest Bureau, Council of Agriculture, Executive Yuan, Taipei, Taiwan, accessed on August, 20; Li, H., Gailbreath, K., Flach, E.J., Taus, N.S., Cooley, J., Keller, J., Russell, G.C., Crawford, T.B., A novel subgroup of rhadinoviruses in ruminants (2005) J. Gen. Virol., 86, pp. 3021-3026; McGeoch, D.J., Gatherer, D., Dolan, A., On phylogenetic relationships among major lineages of the Gammaherpesvirinae (2005) J. Gen. Virol., 86, pp. 307-316; Nei, M., Kumar, S., (2000) Molecular Evolution and Phylogenetics, , Oxford University Press, New York; O{\textquoteright}Toole, D., Li, H., The pathology of malignant catarrhal fever, with an emphasis on ovine herpesvirus 2 (2014) Vet. Pathol., 51, pp. 437-452; Palacios, G., Cowled, C., Bussetti, A.V., Savji, N., Weir, R., Wick, I., Travassos da Rosa, A., Lipkin, W.I., Rapid molecular strategy for orbivirus detection and characterization (2011) J. Clin. Microbiol., 49, pp. 2314-2317; Pitra, C., Fickel, J., Meijaard, E., Groves, P.C., Evolution and phylogeny of old world deer (2004) Mol. Phylogenet. Evol., 33, pp. 880-895; Plowright, W., Ferris, R.D., Scott, G.R., Blue wildebeest and the aetiological agent of bovine malignant catarrhal fever (1960) Nature, 188, pp. 1167-1169; Russell, G.C., Stewart, J.P., Haig, D.M., Malignant catarrhal fever: A review (2009) Vet. J., 179, pp. 324-335; Tamura, K., Stecher, G., Peterson, D., Filipski, A., Kumar, S., MEGA6: Molecular evolutionary genetics analysis version 6.0 (2013) Mol. Biol. Evol., 30, pp. 2725-2729; Vandevanter, D.R., Warrener, P., Bennett, L., Schultz, E.R., Coulter, S., Garber, R.L., Rose, T.M., Detection and analysis of diverse herpesviral species by consensus primer PCR (1996) J. Clin. Microbiol., 34, pp. 1666-1671; Yen, S.C., Wang, Y., Ou, H.Y., Habitat of the vulnerable Formosan sambar deer Rusa unicolor swinhoii in Taiwan (2014) Oryx, 48, pp. 232-240",
year = "2018",
doi = "10.1292/jvms.17-0477",
language = "English",
volume = "80",
pages = "810--813",
journal = "Journal of Veterinary Medical Science",
issn = "0916-7250",
publisher = "Japanese Society of Veterinary Science",
number = "5",
}