Electrophysiological changes in lipaemia retinalis

Chao Kung Lu; Shih Jen Chen; Dau Ming Niu; Chia Chen Tsai; Fenq Lih Lee; Wen Ming Hsu

doi:10.1016/j.ajo.2004.12.021

Electrophysiological changes in lipaemia retinalis

Chao Kung Lu, Shih Jen Chen, Dau Ming Niu, Chia Chen Tsai, Fenq Lih Lee, Wen Ming Hsu

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.

Original language	English
Pages (from-to)	1142-1145
Number of pages	4
Journal	American Journal of Ophthalmology
Volume	139
Issue number	6
DOIs	https://doi.org/10.1016/j.ajo.2004.12.021
Publication status	Published - Jun 2005
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.ajo.2004.12.021

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title = "Electrophysiological changes in lipaemia retinalis",

abstract = "PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.",

author = "Lu, {Chao Kung} and Chen, {Shih Jen} and Niu, {Dau Ming} and Tsai, {Chia Chen} and Lee, {Fenq Lih} and Hsu, {Wen Ming}",

year = "2005",

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doi = "10.1016/j.ajo.2004.12.021",

language = "English",

volume = "139",

pages = "1142--1145",

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T1 - Electrophysiological changes in lipaemia retinalis

AU - Lu, Chao Kung

AU - Chen, Shih Jen

AU - Niu, Dau Ming

AU - Tsai, Chia Chen

AU - Lee, Fenq Lih

AU - Hsu, Wen Ming

PY - 2005/6

Y1 - 2005/6

N2 - PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.

AB - PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.

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ER -

Electrophysiological changes in lipaemia retinalis

Abstract

ASJC Scopus subject areas

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