Electrocorticogram changes during corpus callosotomy for uncontrolled symptomatic generalized epilepsy

Hann Yeh Shyu, Ji Ho Lin, Shang Yeong Kwan, Kai Ping Chang, Chun Hing Yiu, Tai Tong Wong

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We report a 19-year-old man who presented to our facility with medically intractable, symptomatic generalized epilepsy manifesting as generalized tonic-clonic seizures (GTCs). Before he underwent an anterior callosotomy (6 cm), these seizures, which he had experienced for 11 years, seemed to have a left-sided focal origin. Intraoperatively, no epileptiform discharges were found on the electrocorticogram (ECoG) performed prior to sectioning, but more than 10 left-sided seizures were recorded after sectioning. In the 10 years since surgery, the patient's seizures have remained generalized; however, the frequency and severity of the seizures have decreased. These findings indicate that the presence of electrocorticographic seizures, as measured by ECoG immediately following callosotomy, may not predict a poor surgical outcome, even though such a finding might be indicative of epileptogenicity in general.

Original languageEnglish
Pages (from-to)132-134
Number of pages3
JournalJournal of Clinical Neuroscience
Issue number1
Publication statusPublished - Jan 2010
Externally publishedYes


  • Callosotomy
  • Corpus callosum
  • Electrocorticogram
  • Generalized tonic-clonic seizure

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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