@article{5d4a3e31c6444ddf8c20c42814b1fb8e,
title = "Effects of testosterone on the metabolism of arachidonic acid by aortas and platelets in rats",
abstract = "The effects of testosterone on the prostacyclin production by aortas and the biosynthesis of thromboxane in platelets of male rats in vivo were investigated.Testosterone significantly inhibits prostacyclin production by aortas. However, no significant effect on thromboxane biosynthesis in platelets is observed. The results provide a plausible explanation for the thrombogenic effect of testosterone in rats.",
author = "Chang, {Wen Chang} and Junko Nakao and Tai, {Hsin Hsiung} and Murota, {Sei itsu}",
note = "Funding Information: The authors wish to thank Ono Pharmaceutical Co., Ltd., Osaka, Japan for its financial support to W.C.C. and for the generous gifts of standard prostaglandins and thromboxane. Thanks are also due to Japan Upjohn Limited, Tokyo, Japan and the Upjohn Co., Kalamazoo, MI, U.S.A. for the generous gift of depo-testosterone cypionate. This work was supported in part by grants from the National Institutes of Health (GM-30380) and the American Heart Association (81-1152).",
year = "1982",
month = nov,
doi = "10.1016/0262-1746(82)90030-0",
language = "English",
volume = "9",
pages = "495--501",
journal = "Prostaglandins, Leukotrienes and Medicine",
issn = "0262-1746",
publisher = "Churchill Livingstone",
number = "5",
}