Effects of serum leptin on the effectiveness of weight loss

Mei Chich Huang, Ming-Che Hsieh, Fang Hsuean Liao, Chin Fa Chen, Hui Ching Liu, Yi Wen Chien

Research output: Contribution to journalArticlepeer-review


The purpose of this study was to assess the correlation of serum leptin concentration with the effectiveness of weight loss. Eighteen subjects (four males and fourteen females) were provided with 1200 kcal/day (CHO, 55%; fat, 20%; and protein, 25%) commercial packages were used to replace two meals for 8 weeks; and patients were followed-up for 3 months. Subjects were aged 39 ± 1.7 years, with an initial body weight of 73.0 ± 2.4 kg, body mass index (BMI) of 28.2 ± 0.8 kg/m2, and body fat mass percentage of 33.1% ± 1.5%. After 4 weeks in the weight loss program, the average weight loss was 2.6 kg. Body weight, fat mass, muscle mass, BMI, total body water, protein weight, basal metabolic rate (BMR), and body fat percentage all significantly decreased (p

Original languageEnglish
Pages (from-to)168-175
Number of pages8
JournalNutritional Sciences Journal
Issue number3
Publication statusPublished - Sept 2004


  • Leptin
  • Leptin concentration change
  • Low-energy diet
  • Obesity
  • Weight loss

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science


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