Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Po Liang Lin; Hsu Wei Fang; Tiffany Tseng; Wun Hsing Lee

doi:10.1016/j.matlet.2006.10.064

Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Po Liang Lin, Hsu Wei Fang, Tiffany Tseng, Wun Hsing Lee

Research output: Contribution to journal › Article › peer-review

74 Citations (Scopus)

Abstract

Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

Original language	English
Pages (from-to)	3009-3013
Number of pages	5
Journal	Materials Letters
Volume	61
Issue number	14-15
DOIs	https://doi.org/10.1016/j.matlet.2006.10.064
Publication status	Published - Jun 1 2007
Externally published	Yes

Keywords

Cell proliferation
Composite
Hydroxyapatite
Mechanical strength
Polylactic acid

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2006.10.064

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title = "Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials",

abstract = "Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.",

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AU - Lin, Po Liang

AU - Fang, Hsu Wei

AU - Tseng, Tiffany

AU - Lee, Wun Hsing

PY - 2007/6/1

Y1 - 2007/6/1

N2 - Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

AB - Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

KW - Cell proliferation

KW - Composite

KW - Hydroxyapatite

KW - Mechanical strength

KW - Polylactic acid

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JO - Materials Letters

JF - Materials Letters

IS - 14-15

ER -

Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Abstract

Keywords

ASJC Scopus subject areas

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