Abstract
Aim: To investigate the effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer. Methods: Sprague-Dawley rats were randomly divided into four groups: sham operation without ginkgo, sham operation with ginkgo, duodenal ulcer without ginkgo, and duodenal ulcer with ginkgo. Rats with duodenal ulcer were induced by 500 mL/L acetic acid. Rats with ginkgo were intravenously injected with Ginkgo biloba extract from the tail at a dose of 0.5 mg/(kg.d) for 7 and 14 days. Results: Pathological result showed that duodenal ulcer rats with ginkgo improved mucosal healing and inflammation compared with those without ginkgo after 7 d treatment. After 14 d treatment, duodenal ulcer rats with ginkgo significantly increased weight gain (34.0±4.5 g versus 24.5±9.5 g, P2 concentration significantly increased by 129% (P
| Original language | English |
|---|---|
| Pages (from-to) | 560-566 |
| Number of pages | 7 |
| Journal | World Journal of Gastroenterology |
| Volume | 10 |
| Issue number | 4 |
| Publication status | Published - Feb 15 2004 |
ASJC Scopus subject areas
- Gastroenterology