Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients

Hua Ting; Shin Da Lee; Ai Hui Chung; Ming Lung Chuang; Gin Den Chen; Jiuan Miaw Liao; Chen Lurng Chang; Thomas S.M. Chiou; Tzer Bin Lin

doi:10.1016/j.autneu.2005.05.007

Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients

Hua Ting, Shin Da Lee, Ai Hui Chung, Ming Lung Chuang, Gin Den Chen, Jiuan Miaw Liao, Chen Lurng Chang, Thomas S.M. Chiou, Tzer Bin Lin

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p < 0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p < 0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.

Original language	English
Pages (from-to)	74-80
Number of pages	7
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	121
Issue number	1-2
DOIs	https://doi.org/10.1016/j.autneu.2005.05.007
Publication status	Published - Aug 31 2005
Externally published	Yes

Keywords

Autonomic nervous system
Endoscopic transthoracic sympathectomy
Gas exchange
Hemodynamics
Sympathetic cardiac nerve

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1016/j.autneu.2005.05.007

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title = "Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients",

abstract = "The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p < 0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p < 0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.",

keywords = "Autonomic nervous system, Endoscopic transthoracic sympathectomy, Gas exchange, Hemodynamics, Sympathetic cardiac nerve",

author = "Hua Ting and Lee, {Shin Da} and Chung, {Ai Hui} and Chuang, {Ming Lung} and Chen, {Gin Den} and Liao, {Jiuan Miaw} and Chang, {Chen Lurng} and Chiou, {Thomas S.M.} and Lin, {Tzer Bin}",

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T1 - Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients

AU - Ting, Hua

AU - Lee, Shin Da

AU - Chung, Ai Hui

AU - Chuang, Ming Lung

AU - Chen, Gin Den

AU - Liao, Jiuan Miaw

AU - Chang, Chen Lurng

AU - Chiou, Thomas S.M.

AU - Lin, Tzer Bin

PY - 2005/8/31

Y1 - 2005/8/31

N2 - The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p < 0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p < 0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.

AB - The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p < 0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p < 0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.

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KW - Hemodynamics

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Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients

Abstract

Keywords

ASJC Scopus subject areas

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