Down-Regulation of the Oncogene PTTG1 via the KLF6 Tumor Suppressor during Induction of Myeloid Differentiation

Medicine & Life Sciences

• Kruppel-Like Factor 6 100%
• Pituitary Neoplasms 60%
• Oncogenes 52%
• Down-Regulation 38%
• phorbol-12-myristate 32%
• Acetates 27%
• Neoplasms 17%
• HL-60 Cells 10%
• Acute Myeloid Leukemia 8%
• Protein Kinase C 8%
• Tumor Suppressor Proteins 6%
• Gene Expression 5%
• Protein C Inhibitor 5%
• Proto-Oncogenes 5%
• Differentiation Antigens 5%
• Mitogen-Activated Protein Kinase Kinases 5%
• Protein Kinase Inhibitors 4%
• Myeloid Cells 4%
• Hematologic Neoplasms 4%
• Small Interfering RNA 3%
• Monocytes 3%
• Leukemia 3%
• Cell Differentiation 3%
• Leukocytes 3%
• Binding Sites 3%
• Transcription Factors 3%
• Macrophages 3%
• Cell Proliferation 3%
• Messenger RNA 2%
• Therapeutics 2%
• Pharmaceutical Preparations 1%
• Proteins 1%

Chemical Compounds

• Phorbol 75%
• Phorbol 13-Acetate 12-Myristate 41%
• Protein Kinase C Inhibitor 22%
• Tumor Suppressor Protein 21%
• Oncogenic 19%
• Small Interfering RNA 19%
• Phosphotransferase Inhibitor 17%
• Marker 12%
• Protein 11%
• Binding Site 9%
• Drug 7%
• Reduction 6%
• Application 4%

Agriculture & Biology

• oncogenes 68%
• neoplasms 42%
• acetates 19%
• genes 19%
• myeloid leukemia 12%
• protein kinase C 9%
• mitogen-activated protein kinase 9%
• tumor suppressor proteins 7%
• proto-oncogenes 5%
• cells 5%
• leukemia 4%
• monocytes 4%
• cell differentiation 4%
• cell proliferation 3%
• leukocytes 3%
• macrophages 3%
• phosphotransferases (kinases) 3%
• binding sites 3%
• therapeutics 3%
• transcription factors 3%
• promoter regions 3%
• drugs 2%
• tissues 1%
• proteins 1%