Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia

Giun Yi Hung; Tzeon Jye Chiou; Chia Yau Chang; Hao Wei Teng; Po Min Chen; Betau Hwang

doi:10.1532/IJH97.A10419

Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia

Giun Yi Hung, Tzeon Jye Chiou, Chia Yau Chang, Hao Wei Teng, Po Min Chen, Betau Hwang

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We report the results of unrelated cord blood transplantation (CBT) in a 12-year-old boy with Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase and a high body weight (68.5 kg at transplantation). Only 1 of the 2 units used engrafted. This unit was not human leukocyte antigen (HLA) class II identical with the patient and had a much larger number of nucleated cells than the other unit (approximately 2.4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan.

Original language	English
Pages (from-to)	159-161
Number of pages	3
Journal	International Journal of Hematology
Volume	82
Issue number	2
DOIs	https://doi.org/10.1532/IJH97.A10419
Publication status	Published - Aug 1 2005
Externally published	Yes

Keywords

Chronic myelogenous leukemia
Cord blood transplantation
Double units
High body weight

ASJC Scopus subject areas

Hematology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1532/IJH97.A10419

Cite this

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title = "Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia",

abstract = "We report the results of unrelated cord blood transplantation (CBT) in a 12-year-old boy with Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase and a high body weight (68.5 kg at transplantation). Only 1 of the 2 units used engrafted. This unit was not human leukocyte antigen (HLA) class II identical with the patient and had a much larger number of nucleated cells than the other unit (approximately 2.4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan.",

keywords = "Chronic myelogenous leukemia, Cord blood transplantation, Double units, High body weight",

author = "Hung, {Giun Yi} and Chiou, {Tzeon Jye} and Chang, {Chia Yau} and Teng, {Hao Wei} and Chen, {Po Min} and Betau Hwang",

note = "Funding Information: The authors gratefully acknowledge StemCyte Taiwan, Taipei Veterans General Hospital Hueih-Chung Medical Foundation, the Childhood Cancer Foundation of R.O.C., Raising Children Medical Foundation, and Taiwan Cancer Clinical Research and Development Foundation for their support in this case study.",

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doi = "10.1532/IJH97.A10419",

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AU - Hung, Giun Yi

AU - Chiou, Tzeon Jye

AU - Chang, Chia Yau

AU - Teng, Hao Wei

AU - Chen, Po Min

AU - Hwang, Betau

N1 - Funding Information: The authors gratefully acknowledge StemCyte Taiwan, Taipei Veterans General Hospital Hueih-Chung Medical Foundation, the Childhood Cancer Foundation of R.O.C., Raising Children Medical Foundation, and Taiwan Cancer Clinical Research and Development Foundation for their support in this case study.

PY - 2005/8/1

Y1 - 2005/8/1

N2 - We report the results of unrelated cord blood transplantation (CBT) in a 12-year-old boy with Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase and a high body weight (68.5 kg at transplantation). Only 1 of the 2 units used engrafted. This unit was not human leukocyte antigen (HLA) class II identical with the patient and had a much larger number of nucleated cells than the other unit (approximately 2.4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan.

AB - We report the results of unrelated cord blood transplantation (CBT) in a 12-year-old boy with Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase and a high body weight (68.5 kg at transplantation). Only 1 of the 2 units used engrafted. This unit was not human leukocyte antigen (HLA) class II identical with the patient and had a much larger number of nucleated cells than the other unit (approximately 2.4:1). To our knowledge, this case report is the first to describe successful CBT from two unrelated donors to a cancer patient, who had the highest body weight among CBT recipients in Taiwan.

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KW - Cord blood transplantation

KW - Double units

KW - High body weight

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Double-unit unrelated cord blood transplantation for chronic myelogenous leukemia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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