Dose-response relationship between ischemic heart disease mortality and long-term arsenic exposure

Chien Jen Chen; Hung Yi Chiou; Ming Hsi Chiang; Li Ju Lin; Tong Yuan Tai

Dose-response relationship between ischemic heart disease mortality and long-term arsenic exposure

Chien Jen Chen, Hung Yi Chiou, Ming Hsi Chiang, Li Ju Lin, Tong Yuan Tai

Research output: Contribution to journal › Article › peer-review

Abstract

The cardiovascular effects of inorganic arsenic have been documented, but the dose-response relationship between ischemic heart disease (ISHD) and long-term arsenic exposure remains to be elucidated. Mortality rates from ISHD among residents in 60 villages of the area in Taiwan with endemic arseniasis from 1973 through 1986 were analyzed to examine their association with arsenic concentration in drinking water. Based on 1 355 915 person- years and 217 ISHD deaths, the cumulative ISHD mortalities from birth to age 79 years were 3.4%, 3.5%, 4.7%, and 6.6%, respectively, for residents who lived in villages in which the median arsenic concentrations in drinking water were

Original language	English
Pages (from-to)	504-510
Number of pages	7
Journal	Arteriosclerosis, Thrombosis, and Vascular Biology
Volume	16
Issue number	4
Publication status	Published - 1996
Externally published	Yes

Keywords

arsenic
blackfoot disease
ischemic heart disease

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

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title = "Dose-response relationship between ischemic heart disease mortality and long-term arsenic exposure",

abstract = "The cardiovascular effects of inorganic arsenic have been documented, but the dose-response relationship between ischemic heart disease (ISHD) and long-term arsenic exposure remains to be elucidated. Mortality rates from ISHD among residents in 60 villages of the area in Taiwan with endemic arseniasis from 1973 through 1986 were analyzed to examine their association with arsenic concentration in drinking water. Based on 1 355 915 person- years and 217 ISHD deaths, the cumulative ISHD mortalities from birth to age 79 years were 3.4%, 3.5%, 4.7%, and 6.6%, respectively, for residents who lived in villages in which the median arsenic concentrations in drinking water were ",

keywords = "arsenic, blackfoot disease, ischemic heart disease",

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AU - Chen, Chien Jen

AU - Chiou, Hung Yi

AU - Chiang, Ming Hsi

AU - Lin, Li Ju

AU - Tai, Tong Yuan

PY - 1996

Y1 - 1996

N2 - The cardiovascular effects of inorganic arsenic have been documented, but the dose-response relationship between ischemic heart disease (ISHD) and long-term arsenic exposure remains to be elucidated. Mortality rates from ISHD among residents in 60 villages of the area in Taiwan with endemic arseniasis from 1973 through 1986 were analyzed to examine their association with arsenic concentration in drinking water. Based on 1 355 915 person- years and 217 ISHD deaths, the cumulative ISHD mortalities from birth to age 79 years were 3.4%, 3.5%, 4.7%, and 6.6%, respectively, for residents who lived in villages in which the median arsenic concentrations in drinking water were

AB - The cardiovascular effects of inorganic arsenic have been documented, but the dose-response relationship between ischemic heart disease (ISHD) and long-term arsenic exposure remains to be elucidated. Mortality rates from ISHD among residents in 60 villages of the area in Taiwan with endemic arseniasis from 1973 through 1986 were analyzed to examine their association with arsenic concentration in drinking water. Based on 1 355 915 person- years and 217 ISHD deaths, the cumulative ISHD mortalities from birth to age 79 years were 3.4%, 3.5%, 4.7%, and 6.6%, respectively, for residents who lived in villages in which the median arsenic concentrations in drinking water were

KW - arsenic

KW - blackfoot disease

KW - ischemic heart disease

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IS - 4

ER -

Dose-response relationship between ischemic heart disease mortality and long-term arsenic exposure

Abstract

Keywords

ASJC Scopus subject areas

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