Dissociated roles of the middle frontal gyri in the processing of Chinese characters

Chia Li Liu, Chih Wei Hue, Chien Chung Chen, Kai Hsiang Chuang, Keng Chen Liang, Yao Hung Wang, Chang Wei Wu, Jyh Horng Chen

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)


The present study examined a hypothesis that the right middle frontal gyrus participates in processing orthography of Chinese characters, while the left middle frontal gyrus mediates access to phonology and semantics. Brain activation during three character tasks, which required processing orthography, phonology, or semantics of Chinese characters, respectively, was measured by functional magnetic resonance imaging. Comparable neural activity in the right middle frontal gyrus was observed in all three character tasks that always demand orthographical processing. In contrast, the left middle frontal gyrus showed greater activation in the phonological and semantic tasks than in the orthographic task. These results suggest that the right and left middle frontal gyrus have dissociable functions in achieving Chinese character recognition.

Original languageEnglish
Pages (from-to)1397-1401
Number of pages5
Issue number13
Publication statusPublished - Sept 1 2006
Externally publishedYes


  • Blood oxygenation level-dependent
  • Functional magnetic resonance imaging
  • Language
  • Orthography
  • Phonology
  • Semantics
  • Word recognition

ASJC Scopus subject areas

  • Neuroscience(all)


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