Dissemination of Proteus mirabilis isolates harboring CTX-M-14 and CTX-M-3 β-lactamases at 2 hospitals in Taiwan

  • Lii Tzu Wu
  • , Hwa Jen Wu
  • , Jing Gung Chung
  • , Yin Ching Chuang
  • , Kuo Chen Cheng
  • , Wen-Liang Yu

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

From February to June 2003, 111 clinical isolates of Proteus mirabilis were mainly isolated from patients with respiratory or urinary tract infections hospitalized at 3 district hospitals (A, B, C) in central Taiwan. Among them, 34 (30.6%) strains, isolated within 2 hospitals (A and B), exhibited nonsusceptibility to cefotaxime with significant reduction of MIC (≥3 log2 dilution) by the effect of clavulanic acid, which confirmed the phenotype of extended-spectrum β-lactamases (ESBLs). These ESBL producers were coresistant to gentamicin, isepamicin, and amikacin, but remained susceptible to ceftazidime (MIC, ≤0.5 μg/mL) and meropenem (MIC,

Original languageEnglish
Pages (from-to)89-94
Number of pages6
JournalDiagnostic Microbiology and Infectious Disease
Volume54
Issue number2
DOIs
Publication statusPublished - Feb 2006

Keywords

  • CTX-M
  • Proteus mirabilis
  • β-Lactamases

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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