TY - JOUR
T1 - Dilated left atrium and pulmonary veins in patients with calcified coronary artery
T2 - A potential contributor to the genesis of atrial fibrillation
AU - Pan, Nan Hung
AU - Tsao, Hsuan Ming
AU - Chang, Nen Chung
AU - Lee, Chih Ming
AU - Chen, Yi Jen
AU - Chen, Shih Ann
PY - 2009/2
Y1 - 2009/2
N2 - Ischemic Remodeling of Left Atrium and Pulmonary Vein. Introduction: Coronary artery disease (CAD) is an important etiology of atrial fibrillation (AF). Coronary artery calcification is a marker of coronary atherosclerosis and coronary events. The purpose of this study was to investigate whether larger left atrium (LA) and pulmonary veins (PVs) were seen by multidetector computed tomography (MDCT) scans in those patients with higher coronary calcium scores. Methods and Results: A total of 166 patients undergoing MDCT for general check-up (n = 128, 77%) or suspected CAD (n = 38, 23%) were enrolled and divided into a control (calcium score = 0, n = 60), medium calcium score (calcium score = 100∼400, n = 47), and high calcium score (calcium score >400, n = 59) groups. Diameters and areas of the LA, left atrial appendage (LAA), and PVs were measured by MDCT. The high calcium score group had significantly larger PVs diameters, LAA orifice area (1.9 ± 1.4 cm 2, 0.9 ± 0.5 cm 2, 0.8 ± 0.4 cm 2, P < 0.005), LA anterior-posterior distance (32.2 ± 6.8 mm, 30.4 ± 6.5 mm, 27.3 ± 6.0 mm, P < 0.05), and transverse distance (52.6 ± 7.3 mm, 50.2 ± 9 mm, 49.5 ± 4.6 mm, P < 0.05) than the medium calcium score and control groups. Six (3.6%) patients with paroxysmal AF had higher calcium scores and larger diameters of LA, LAA, and PVs than those (96.4%) without paroxysmal AF. Two patients in the high calcium score group had calcified PVs localized to the right upper and left upper PVs. The incidence of calcified PVs was 1.2% for the total patients and 3.3% for the high calcium score patients. Conclusion: In the presence of high calcium scores in this patient population, the LA, LAA, and PVs were enlarged.
AB - Ischemic Remodeling of Left Atrium and Pulmonary Vein. Introduction: Coronary artery disease (CAD) is an important etiology of atrial fibrillation (AF). Coronary artery calcification is a marker of coronary atherosclerosis and coronary events. The purpose of this study was to investigate whether larger left atrium (LA) and pulmonary veins (PVs) were seen by multidetector computed tomography (MDCT) scans in those patients with higher coronary calcium scores. Methods and Results: A total of 166 patients undergoing MDCT for general check-up (n = 128, 77%) or suspected CAD (n = 38, 23%) were enrolled and divided into a control (calcium score = 0, n = 60), medium calcium score (calcium score = 100∼400, n = 47), and high calcium score (calcium score >400, n = 59) groups. Diameters and areas of the LA, left atrial appendage (LAA), and PVs were measured by MDCT. The high calcium score group had significantly larger PVs diameters, LAA orifice area (1.9 ± 1.4 cm 2, 0.9 ± 0.5 cm 2, 0.8 ± 0.4 cm 2, P < 0.005), LA anterior-posterior distance (32.2 ± 6.8 mm, 30.4 ± 6.5 mm, 27.3 ± 6.0 mm, P < 0.05), and transverse distance (52.6 ± 7.3 mm, 50.2 ± 9 mm, 49.5 ± 4.6 mm, P < 0.05) than the medium calcium score and control groups. Six (3.6%) patients with paroxysmal AF had higher calcium scores and larger diameters of LA, LAA, and PVs than those (96.4%) without paroxysmal AF. Two patients in the high calcium score group had calcified PVs localized to the right upper and left upper PVs. The incidence of calcified PVs was 1.2% for the total patients and 3.3% for the high calcium score patients. Conclusion: In the presence of high calcium scores in this patient population, the LA, LAA, and PVs were enlarged.
KW - Atrial fibrillation
KW - Coronary artery calcification
KW - Pulmonary vein
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U2 - 10.1111/j.1540-8167.2008.01290.x
DO - 10.1111/j.1540-8167.2008.01290.x
M3 - Article
C2 - 18803575
AN - SCOPUS:59149105717
SN - 1045-3873
VL - 20
SP - 153
EP - 158
JO - Journal of Cardiovascular Electrophysiology
JF - Journal of Cardiovascular Electrophysiology
IS - 2
ER -