TY - JOUR
T1 - Diffusion Tensor Imaging of the Spinal Cord
AU - Cheng, Sho-Jen
AU - Tsai, Ping-Huei
AU - Lee, Yun-Ting
AU - Li, Yi-Tien
AU - Chung, Hsiao-Wen
AU - Chen, Cheng-Yu
N1 - Funding Information:
HWC receives support in part from the Ministry of Science and Technology under grant MOST 107-2221-E-002-038-MY3. CYC receives support in part from the Ministry of Science and Technology under grant MOST 108-2321-B-038-008.
PY - 2021/5
Y1 - 2021/5
N2 - Spinal cord often is regarded as one of the last territories in the central nervous system where diffusion tensor imaging (DTI) can be used to probe white matter architecture. This article reviews current progress in spinal cord DTI, starting with anatomic properties and technical challenges that make spinal cord DTI a difficult task. Several possibilities offered by advanced pulse sequences that might overcome the difficulties are addressed, with associated trade-offs and limitations. Potential clinical assistance also is discussed in various spinal cord pathologies, such as myelopathy due to external compression, spinal cord tumors, acute ischemia, traumatic injury, and so forth.
AB - Spinal cord often is regarded as one of the last territories in the central nervous system where diffusion tensor imaging (DTI) can be used to probe white matter architecture. This article reviews current progress in spinal cord DTI, starting with anatomic properties and technical challenges that make spinal cord DTI a difficult task. Several possibilities offered by advanced pulse sequences that might overcome the difficulties are addressed, with associated trade-offs and limitations. Potential clinical assistance also is discussed in various spinal cord pathologies, such as myelopathy due to external compression, spinal cord tumors, acute ischemia, traumatic injury, and so forth.
KW - Diffusion tensor imaging
KW - Geometric distortions
KW - Spatial resolution
KW - Spinal cord
KW - White matter integrity
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U2 - 10.1016/j.mric.2021.02.002
DO - 10.1016/j.mric.2021.02.002
M3 - Review article
SN - 1064-9689
VL - 29
SP - 195
EP - 204
JO - Magnetic Resonance Imaging Clinics of North America
JF - Magnetic Resonance Imaging Clinics of North America
IS - 2
ER -