Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET

Wu Huei Hsu; Nan Yung Hsu; Yeh Y. Shen; Ruoh Fang Yen; Chia Hung Kao

doi:10.1081/CNV-120016403

Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET

Wu Huei Hsu, Nan Yung Hsu, Yeh Y. Shen, Ruoh Fang Yen, Chia Hung Kao

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas.

Original language	English
Pages (from-to)	47-52
Number of pages	6
Journal	Cancer Investigation
Volume	21
Issue number	1
DOIs	https://doi.org/10.1081/CNV-120016403
Publication status	Published - 2003
Externally published	Yes

Keywords

18F-fluoro-2-deoxyglucose
Positron emission tomography
Solitary pulmonary metastases

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1081/CNV-120016403

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title = "Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET",

abstract = "The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas.",

keywords = "18F-fluoro-2-deoxyglucose, Positron emission tomography, Solitary pulmonary metastases",

author = "Hsu, {Wu Huei} and Hsu, {Nan Yung} and Shen, {Yeh Y.} and Yen, {Ruoh Fang} and Kao, {Chia Hung}",

year = "2003",

doi = "10.1081/CNV-120016403",

language = "English",

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journal = "Cancer Investigation",

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T1 - Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET

AU - Hsu, Wu Huei

AU - Hsu, Nan Yung

AU - Shen, Yeh Y.

AU - Yen, Ruoh Fang

AU - Kao, Chia Hung

PY - 2003

Y1 - 2003

N2 - The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas.

AB - The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas.

KW - 18F-fluoro-2-deoxyglucose

KW - Positron emission tomography

KW - Solitary pulmonary metastases

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U2 - 10.1081/CNV-120016403

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JO - Cancer Investigation

JF - Cancer Investigation

IS - 1

ER -

Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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