TY - JOUR
T1 - Dicentric Ph1 chromosome
AU - Whang Peng, J.
AU - Knutsen, T. A.
AU - Lee, E. C.
N1 - Funding Information:
2 Tumor Cell Biology Branch, National Cancer Institute, National Institutes of Health, Public Health Service, U.S. Department of Health, Education, and Welfare, Bethesda, Md. 20014.
PY - 1973/1/1
Y1 - 1973/1/1
N2 - Five cases in a chronic myelogenous leukemia series were originally categorized as Ph1 positive and later developed another variant of the Ph1 chromosome. With the new Giemsa banding technique, it appeared to be a dicentric Ph1 chromosome. This chromosome was first noted 23 mth after diagnosis, with the latest appearance at 57 mth. Survival in 3 of the 5 patients after the appearance of the dicentric Ph1 chromosome was 6, 16, and 35 mth; the other 2 are still alive.
AB - Five cases in a chronic myelogenous leukemia series were originally categorized as Ph1 positive and later developed another variant of the Ph1 chromosome. With the new Giemsa banding technique, it appeared to be a dicentric Ph1 chromosome. This chromosome was first noted 23 mth after diagnosis, with the latest appearance at 57 mth. Survival in 3 of the 5 patients after the appearance of the dicentric Ph1 chromosome was 6, 16, and 35 mth; the other 2 are still alive.
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U2 - 10.1093/jnci/51.6.2009
DO - 10.1093/jnci/51.6.2009
M3 - Article
C2 - 4520100
AN - SCOPUS:0015878710
SN - 0027-8874
VL - 51
SP - 2009
EP - 2012
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 6
ER -
